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810-840 / 1000+ resultsresearch Short Peptides Induce Development of Root Hair Nicotiana tabacum
Certain short peptides can increase root hair growth in tobacco plants.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Evaluation of Polyacrylonitrile Nonwoven Mats and Silver–Gold Bimetallic Nanoparticle-Decorated Nonwoven Mats for Potential Promotion of Wound Healing In Vitro and In Vivo and Bone Growth In Vitro
The mats help heal wounds and support bone growth while controlling infections.
research Integrative Proteo‐Transcriptomic Characterization of Androgenetic Alopecia Identifying ME1 ‐Mediated PPAR Signaling as a Potential Mediator
ME1 and PPAR signaling may influence hair loss in androgenetic alopecia.
research Photothermal hydrogels for infection control and tissue regeneration
Photothermal hydrogels can kill bacteria and help heal tissue using light-converted heat.
research Synthesis and structure–activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research Chemical Reactions Occurring in Curing Treatment for Permanent Hair Straightening Using Thioglycolic and Dithioglycolic Acids
Using both TGA and DTDG in hair straightening reduces hair damage compared to using TGA alone.
research Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion
A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.
research Signaling modality within gp130 receptor enhances tissue regeneration
The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction
Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
research Pharmacology and Potential Use of Cyproterone Acetate
Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.
research Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate
Polyamines are important in deciding hair follicle stem cell behavior, affecting hair growth and loss.
research Fluorescence Microscopy Study of the Sorption of Cationic Polymers on Hair
Polymer JR400 sticks to hair but washes off with detergent.
research Targeted gene delivery to skin cells in vivo: A comparative study of liposomes and polymers as delivery vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
research [Purification of recombinant fusion polypeptide hEGF-AWRK6 and effect on wound healing and infection of burn model mice].
EK significantly improved wound healing and reduced infection in burn wounds.
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera.
A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
research Effects of dipotassium glycyrrhizinate on wound healing
Dipotassium glycyrrhizinate helps wounds heal faster, especially in the early stages.
research Recent Progress in Prostaglandin F2αEthanolamide (Prostamide F2α) Research and Therapeutics
New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.
research G4, is a new transgenic mouse model for the polycystic ovaries syndrome
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
research Orders & Contracts
The method effectively delivers vaccines through the skin without needles.
research Changes in Expression and Function of Extrasynaptic GABAAReceptors in the Rat Hippocampus during Pregnancy and after Delivery
Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
research Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways
There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
research 703 Anti-aging potential of gypenosides fraction obtained from naturally grown Gynostemma pentaphyllum in Ulleungdo Island and its 7 new gypenosides
Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene
Researchers found a non-functional sheep keratin gene due to mutations.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Comparative Assessment of Topical Platelet-Rich Plasma and Phenytoin for Diabetic Foot Ulcer Healing in a Rat Model
This study compared the wound-healing efficacy of 1% phenytoin cream and platelet-rich plasma (PRP) gel in a rat model of diabetic foot ulcers. Conducted over 84 days with 20 rats, the study found that both treatments were effective in promoting wound contraction, tissue repair, and re-epithelialization. Although PRP gel showed greater wound contraction and more advanced histological improvements, such as granulation tissue and collagen deposition, the differences between the two treatments were not statistically significant. PRP achieved complete wound closure by day 84, while phenytoin showed near-complete closure. The study suggests that PRP may offer more advanced tissue reconstruction and recommends future research to standardize PRP application protocols.
research p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network
The study explored the roles of p63 and MYC in regulating keratinocyte proliferation and differentiation, revealing that p63 is crucial for maintaining growth and committing to differentiation through distinct mechanisms. Knockdown of p63 led to reduced MYC expression via the Wnt/β-catenin and Notch pathways, decreasing keratinocyte proliferation. A p63-controlled network, involving proteins like FN1, IL1B, CYR61, and JAG1, was essential for initiating differentiation. The research established a novel link between p63 and MYC, suggesting that the balance between MYC-driven cell cycle progression and p63-driven cell adhesion networks could determine skin cell fate.
research Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia
Targeting EGFR may help reduce hair loss from chemotherapy.