28 citations
,
November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
1 citations
,
February 2018 in “The Journal of Sexual Medicine” Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.
5 citations
,
January 2024 in “Reproductive Medicine and Biology” Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.
LGF injections may improve early Peyronie's disease by reducing penile curvature and plaque size.
February 2025 in “International Urology and Nephrology” Peripheral treatments showed some improvement in sexual dysfunction, but central symptoms remain challenging.
January 2025 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” Erectile dysfunction is linked to hormone imbalances and vascular health, requiring personalized treatment approaches.
February 2026 in “The Journal of Sexual Medicine” GnRH agonists can help manage recurrent priapism in sickle cell patients, but long-term safety is unclear.
2 citations
,
May 2019 in “PubMed” Oral finasteride and dutasteride may negatively affect erectile function in rats.
7 citations
,
June 2020 in “Translational Andrology and Urology” Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
15 citations
,
June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
December 2016 in “The Journal of Sexual Medicine” Finasteride for hair loss may cause erectile dysfunction due to tissue fibrosis, and various factors contribute to female sexual dysfunction.
February 2017 in “The Journal of Sexual Medicine” Finasteride for hair loss can cause erectile dysfunction due to tissue fibrosis.
July 2021 in “Indian Journal of Animal Research” Using platelet-rich plasma with primary repair improves healing in penile fractures.
43 citations
,
January 2016 in “International Journal of Andrology” Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
June 2018 in “The Journal of Sexual Medicine” Gray-scale ultrasound effectively detects erectile tissue fibrosis in young men with erectile dysfunction after using finasteride.
January 2020 in “The Journal of Sexual Medicine” Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.
34 citations
,
September 2013 in “Urology” Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
3 citations
,
January 2021 in “Andrology” Low androgen levels reduce nitric oxide production in rat penile cells.
PRP injections with tadalafil and stretching safely improved Peyronie's symptoms but didn't significantly change curvature long-term.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
2 citations
,
January 2023 in “Sexual Medicine” The Men's Training Cup Keep Training masturbation aid may help delay ejaculation and improve erectile function.
July 2023 in “World Journal of Biology Pharmacy and Health Sciences” Trazodone and Chlorpromazine might help treat sexual dysfunction from finasteride and SSRIs.
6 citations
,
September 2010 in “Current Urology Reports” New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.
176 citations
,
June 2017 in “Sexual Medicine Reviews” Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
28 citations
,
May 1994 in “The Journal of Urology” Topical minoxidil not effective for erectile dysfunction treatment.
25 citations
,
February 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
21 citations
,
July 2018 in “The Journal of Sexual Medicine” The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
1 citations
,
February 2024 in “Pharmacognosy Journal” Fenugreek seed extract boosts testosterone and improves male reproductive health without heart side effects.
4 citations
,
December 2014 in “PubMed” Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.