research A rabbit model of hypospadias induced by finasteride
Finasteride can reliably cause hypospadias in rabbits.
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research Administration of Caesalpinia bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
research Metabolic effects of 5α-reductase inhibition in humans
Dutasteride may reduce insulin sensitivity and increase body fat.
research Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism
Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
research Hairless or fertile? Finasteride leads to epididymal changes and infertility in rats
Finasteride may cause infertility in rats by affecting epididymis and sperm function.
research Development of a New Grading Scale for Evaluating Overall Hair Density
A new reliable scale improves accuracy in measuring hair density and treatment response.
research The vellus index: a new method of assessing hair growth
The vellus index is a simple, quick, and reliable method to assess and monitor hair growth, especially in hirsutism.
research Integral characterization of normal and alopecic hair at different degeneration stages by in-situ visible and chemical imaging
Alopecic hair has more irregular structures and chemical changes than normal hair, reducing its strength.
research 175 Reinventing the Selfie: Telemedicine in a Tertiary Referral Sexual Medicine Practice
Telemedicine is effective for sexual medicine consultations.
research Human scalp hair: geometry, biochemistry, growth parameters and mechanical characteristics
A 6-group geometric classification of human scalp hair is more reliable and objective for testing than an 8-group system.
research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Automated digital image analysis (TrichoScan®) for human hair growth analysis: Ease versus errors
TrichoScan often makes mistakes and needs improvement for correct hair growth analysis.
research Abstracts
The model helps improve medical devices by showing how skin deforms under pressure.
research TESTOSTERONE-INDUCED ANDROGENETIC ALOPECIA MICE MODEL: A PRELIMINARY STUDY
A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
research Hyperandrogenism and woman's sexual function
Hyperandrogenism does not affect young women's sexual function.
research Viable terminal scalp hair follicles constitute a necessary and sufficient biological end‐organ that conditions clinical efficacy of finasteride in males with male pattern hair loss without implying reversal of miniaturized follicles
Finasteride works for hair loss by maintaining existing hair follicles, not reversing miniaturization.
research Improvement in androgenetic alopecia in 53-76-year-old men using oral finasteride
Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
research Effectiveness of Exosome Treatment in Androgenetic Alopecia: Outcomes of a Prospective Study
Exosome treatment safely increases hair density in male patients with androgenetic alopecia.
research Androgenic hormone profile in patients with androgenetic alopecia
Androgenetic alopecia in males is linked to hormone levels and the enzyme 5-alpha reductase.
research 5α-Reductase Inhibitors (5ARIs) and Male Reproduction
5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
research Response to the article, “Evaluation of standardized scalp photography on patient perception of hair loss severity, anxiety, and treatment,” by Pathoulas et al
Combining scalp photos with hair density and caliber measurements gives a more accurate assessment of hair loss.
research Change in Prostate Specific Antigen Concentration in Men with Prostate Specific Antigen Less than 2.5 ng/ml Taking Low Dose Finasteride or Dutasteride for Male Androgenetic Alopecia
Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.
research Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson’s Disease
Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
research PRECISE Scale: a quantitative classification for androgenetic alopecia and its application to hair transplantation
The PRECISE scale helps estimate how many grafts are needed for hair transplant based on the severity of hair loss.
research Topical Minoxidil in the Treatment of Male Erectile Dysfunction
Topical minoxidil not effective for erectile dysfunction treatment.
research Study of the international epidemiology of androgenetic alopecia in young caucasian men using photographs from the internet
15.33% of young Caucasian men have severe hair loss, with higher rates in Jewish men and links to age, BMI, and possibly metabolic syndrome.
research Finasteride use in the male infertility population: effects on semen and hormonal parameters
Finasteride may improve sperm count in subfertile men with low sperm count.
research Similar Risk of Sexual Dysfunction in Androgenetic Alopecia Patients Treated With Dutasteride vs. Finasteride: A Retrospective Cohort Database Study
research PROSPECTIVE EVALUATION ON SEXUAL DYSFUNCTION PERSISTENCE, WORSENING OR IMPROVEMENT IN BPH PATIENTS AFTER FINASTERIDE OR DUTASTERIDE TREATMENT
Finasteride and dutasteride can affect sexual function in BPH patients.
research Defining hirsutism in Chinese women: a cross-sectional study
An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.