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5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Erectile dysfunction in young men is caused by both mental and physical factors and needs a personalized treatment approach.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.

Anabolic steroid abuse can cause sexual, fertility, and health problems.

GPCRs are vital for wound healing by affecting cell growth and immune response.

Finasteride is effective for hair loss and prostate issues but may cause lasting side effects.

FFA has higher long-term remission rates than LPP.

Hair loss can be caused by cancer, treatments, or skin conditions, and trichoscopy helps diagnose it.

Transgender individuals face unique skin issues, often due to hormone therapy, requiring specialized and stigma-free dermatologic care.

Personalized, minimally invasive treatments improve urology outcomes.

A runner developed tangled armpit hairs from shirt friction, preventable by shaving or wearing smooth shirts.

Finasteride can cause long-term side effects like sexual dysfunction and depression.

Technology can improve sexual dysfunction in chronic disease patients but faces challenges like cost and accessibility.

The boy's Cushing's Disease was treated successfully, but he developed growth hormone deficiency.

Robotic surgery improves patient safety and surgical quality.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.