24 citations
,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
5 citations
,
January 2021 in “Wiadomości Lekarskie” The method effectively creates acellular dermal matrix from pig skin while preserving structure.
16 citations
,
December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
60 citations
,
February 2014 in “Tissue Engineering Part A” Microporous scaffolds speed up skin healing and regeneration.
July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
1 citations
,
December 2025 in “Stem Cell Research & Therapy” Mesenchymal stem cells help heal wounds by using Cx43 hemichannels to improve tissue repair.
1 citations
,
January 2020 in “VTechWorks (Virginia Tech)” αCT1 improves scar appearance by changing early collagen structure.
8 citations
,
January 2011 in “Experimental and Therapeutic Medicine” Stromal cells in melanoma promote tumor growth and spread.
182 citations
,
June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
4 citations
,
January 2014 in “BioMed Research International” Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
10 citations
,
July 2023 in “World Journal of Stem Cells” The secretome helps protect and regenerate retinal cells by enabling communication between stem cells and retinal cells.
35 citations
,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
14 citations
,
February 2011 in “Experimental dermatology” A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.
5 citations
,
July 2022 in “Frontiers in Medicine” Combining microneedle-delivered ECM and radiofrequency improves skin elasticity and thickness more than ECM alone.
11 citations
,
January 2025 in “Regenerative Therapy” Tissue-engineered scaffolds help heal difficult wounds by supporting cell growth and repair.
2 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
December 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” ECM components regulate β-Catenin activity, affecting wound healing.
January 2023 in “Biomaterials Science” Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
March 2021 in “Research Square (Research Square)” The new 3D sponge-like material helps cells grow and heals wounds effectively.
10 citations
,
January 2012 in “Journal of Oncology” The surrounding tissue plays a crucial role in the growth and spread of skin cancer.
15 citations
,
September 2018 in “Applied Biological Chemistry” Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.
October 2025 in “DOAJ (DOAJ: Directory of Open Access Journals)” Changes in the cochlea's extracellular matrix contribute to age-related hearing loss.
9 citations
,
August 2005 in “Archives of Dermatological Research” Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
62 citations
,
March 2015 in “PLOS ONE” Pre-seeding scaffolds with fibroblasts improves skin wound healing.
10 citations
,
January 2018 in “Organogenesis” Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Actin filaments help stabilize and integrate cell membranes during transfer.
January 2025 in “Regenerative Biomaterials” The cerium-polypeptide hydrogel effectively heals drug-resistant bacterial wounds by fighting bacteria, reducing inflammation, and promoting tissue repair.
2 citations
,
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Rare Gli1+ fibroblasts are crucial for skin wound healing.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.