TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
January 2023 in “Theranostics” A patch with curcumin-zinc can improve hair growth and health by delivering beneficial particles to the skin, increasing hair follicles, and reversing effects of a hair loss hormone.
September 2025 in “Pharmaceutics” Combining plant extracts with nanotechnology may improve hair loss treatments.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
194 citations
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March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
44 citations
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January 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
40 citations
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January 2013 in “International journal of trichology” Perifollicular erythema can indicate active frontal fibrosing alopecia.
33 citations
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July 1992 in “Journal of Investigative Dermatology” Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
30 citations
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May 2016 in “International Journal of Cosmetic Science” Hair loss in women links to inflammation around hair follicles.
30 citations
,
October 1994 in “Journal of Cutaneous Pathology” Multiple perifollicular fibromas may actually be unrecognized cases of Birt-Hogg-Dubé syndrome.
21 citations
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March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
17 citations
,
January 2010 in “Acta Dermato Venereologica” EGFR inhibitors can cause yellowish skin eruptions.
13 citations
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January 2013 in “International Journal of Trichology” Inflammation around hair follicles may worsen hair loss; evaluating and treating it can improve transplant results.
12 citations
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April 2004 in “PubMed” A rare skin condition in a baby showed unusual fat and hair follicle changes.
12 citations
,
February 1999 in “British Journal of Dermatology” Minoxidil increased small openings in blood vessel walls near growing hair in rats.
9 citations
,
October 2015 in “Postgraduate Medical Journal” Scurvy can cause skin issues and is treatable with vitamin C.
9 citations
,
January 2002 in “Dermatology” Reduced CD44 expression may cause abnormal hyaluronate buildup in cutaneous myxoma.
7 citations
,
March 2003 in “PubMed” The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
2 citations
,
November 2018 in “Veterinary Dermatology” Poodles' hair changes aren't always linked to calcium, and special staining is needed to detect true calcium deposits.
1 citations
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February 2023 in “American Journal of Dermatopathology”
1 citations
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September 2021 in “Journal of The American Academy of Dermatology” Hair loss in both Androgenetic Alopecia and Alopecia Areata is often accompanied by inflammation around hair follicles, but the location and severity of this inflammation varies.
April 2026 in “Brazilian Journal of Hair Health” Perifollicular fibrosis hinders hair regrowth in androgenetic alopecia, and new treatments targeting fibrosis are needed.
February 2026 in “Cosmetics” Perifollicular elastolysis is poorly understood, with limited treatment options and inconsistent results.
January 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” Early biopsy and targeting inflammation can improve treatment for hair loss in androgenetic alopecia.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” Early diagnosis and targeted anti-inflammatory treatments can improve outcomes in androgenetic alopecia with perifollicular inflammation and fibrosis.
October 2025 in “Research Square (Research Square)” Enhancing blood vessel interactions with hair cells may help treat hair loss and skin aging.
September 2024 in “Journal of Ethnopharmacology” Terminalia bellirica extracts effectively promote hair regrowth and treat androgenetic alopecia.
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
May 2024 in “Nano letters” Polydopamine and quercetin together can speed up hair regrowth.
September 2022 in “The American Journal of Dermatopathology” Blocking IL-17 might help treat the hair loss condition Lichen planopilaris.