21 citations
,
December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
17 citations
,
November 2000 in “Journal of the American Pharmaceutical Association” The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Kuntai capsules combined with nilestriol tablets effectively reduce perimenopausal symptoms and improve hormone levels.
3 citations
,
October 2015 in “EFSA supporting publications” Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.
June 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
January 2013 in “kerbala journal of pharmaceutical sciences” Low zinc levels are strongly linked to hair loss in adult premenopausal women.
89 citations
,
February 2002 in “Australasian journal of dermatology” A premenopausal woman had hair loss and skin issues, treated with topical steroids.
10 citations
,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
September 2025 in “Australian Journal of Herbal and Naturopathic Medicine” Ashwagandha is safe and effective for reducing perimenopausal symptoms.
19 citations
,
March 2018 in “JAMA” Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.
15 citations
,
October 2003 in “Annals of Oncology” Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.
11 citations
,
February 2013 in “Clinical Endocrinology” A small number of premenopausal female blood donors had high prolactin levels, often due to stress, and retesting is recommended to prevent misdiagnosis.
January 2025 in “Human Reproduction Open” 25% of premenopausal women with Type 1 diabetes have undiagnosed androgen excess disorders.
April 2019 in “International Journal of Research in Dermatology” Most women with hirsutism have mild symptoms and often experience acne, menstrual irregularities, and obesity.
22 citations
,
January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
4 citations
,
January 2015 in “Journal of Mid-life Health” The most common skin problems in perimenopausal women in South India are infections, eczemas, and acne, possibly worsened by external factors and lifestyle practices.
January 2014 in “Healthy aging research” Polycystic ovarian disease symptoms can continue after menopause, making diagnosis and management in older women challenging.
502 citations
,
February 2008 in “The Journal of Clinical Endocrinology & Metabolism” Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
70 citations
,
February 2012 in “Human Reproduction” Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.
16 citations
,
January 2007 in “Archives of Iranian Medicine” Polycystic ovary syndrome is the main cause of hirsutism in premenopausal Iranian women.
2 citations
,
January 2014 in “Journal of Integrated Health Sciences” Obesity is strongly linked to the severity of hirsutism in women.
September 2025 in “International Journal of Women’s Dermatology” Oral spironolactone effectively promotes hair growth in premenopausal women but may cause irregular menstruation.
January 2017 in “Egyptian Journal of Dermatology and Venereology” Iron deficiency may contribute to chronic hair loss in premenopausal women.
2 citations
,
May 2017 in “Maturitas” Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
22 citations
,
January 2019 in “Climacteric” Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.
1 citations
,
August 2018 in “Journal of the American Academy of Dermatology” A young woman developed facial bumps before hair loss, which is unusual for her condition.
November 2025 in “Dermatology and Therapy” The drinkable supplement increased hair growth and was safe for women with hair loss.
Women with female pattern hair loss may have a higher risk of metabolic syndrome.
January 2020 in “Advances in Sexual Medicine” Female pattern hair loss does not significantly affect sexual dysfunction.
7 citations
,
January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.