20 citations
,
February 2019 in “Genes” The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
20 citations
,
February 2016 in “American Journal of Pathology” The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
20 citations
,
January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
20 citations
,
June 2012 in “Human Reproduction” Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
19 citations
,
April 2020 in “Psychological Medicine” The study found three different timing patterns of symptoms in women with premenstrual dysphoric disorder.
19 citations
,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
19 citations
,
February 2018 in “Cell Stem Cell” Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.
19 citations
,
October 2012 in “Frontiers of Hormone Research” Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.
19 citations
,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
19 citations
,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
18 citations
,
January 2015 in “Journal of obesity and weight loss therapy” Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.
18 citations
,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
18 citations
,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
17 citations
,
November 2000 in “Journal of the American Pharmaceutical Association” The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
16 citations
,
January 2023 in “Cureus” PCOS in teens causes hormonal imbalances, irregular periods, and can lead to infertility and other health issues.
16 citations
,
February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
16 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Children with HIV often have skin problems that can indicate the severity of their immune system damage.
16 citations
,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
16 citations
,
January 2007 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.
15 citations
,
May 2013 in “American Journal of Medical Genetics - Part A” People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
14 citations
,
January 2024 in “Theranostics” Intranasal delivery of gene therapy shows promise for treating ischemic stroke.
14 citations
,
February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
13 citations
,
June 2020 in “International Journal of Dermatology” A rare scalp condition mainly in older women can be treated with various alternatives to steroids, which may have fewer side effects.
13 citations
,
January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
13 citations
,
June 2006 in “Pituitary” A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.
12 citations
,
May 2017 in “Pharmacology & therapeutics” Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
11 citations
,
March 2024 in “Cell and Tissue Research” Telocytes have potential in therapy and tissue regeneration, but challenges in identification and cultivation remain.
11 citations
,
May 1990 in “Journal of Dermatological Science” Diazoxide applied to the skin can increase hair growth without harmful side effects.
10 citations
,
July 2021 in “International Journal of Rheumatic Diseases” Lupus patients' body image issues significantly affect their mental health and need more support.