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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Recognizing IPPP is crucial to prevent misdiagnosis and unnecessary treatments.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

FERONIA is crucial for plant growth, pollen tube reception, and sugar signaling.

Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.

Corneal cells can transform into skin and hair cells through specific signals.

Finasteride and DEHP exposure during development can change reproductive markers in rats.

Inhibiting Bmp signaling disrupts hair growth and differentiation.

Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

Targeting the p300/AR axis may help treat polycystic ovary syndrome.

Two siblings were the first reported cases of inheriting both eye coloboma and loose anagen syndrome together.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Monilethrix is linked to the type II keratin gene on chromosome 12q13.

ARHGEF3 is essential for proper hair follicle development in mice.

Protein extract from embryonic skin can create new hair follicles in adult life, primarily through effects on fibroblasts.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

The hair defect is due to abnormal inner root sheath keratinization.

Low IRES/Cap translation is linked to higher stem cell potential.

A new genetic tool improves the study of hair growth and potential hair disorder treatments.

Mutations in the SNRPE gene cause hereditary hair loss.

EPI-NCSCs from hair follicles may help treat brain development issues in mice.

A dark-haired Chinese girl had hair that looked banded under certain light but was normal under a microscope.

A new severe form of monilethrix syndrome includes hair loss, scalp itching, cataracts, and distinct facial features.