research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
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research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: Oral Presentations
NIPT can help detect potential maternal cancer, and GIPXplore can identify immune diseases in pregnancies.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research The Polycystic Ovary Syndrome - Challenges and Opportunities in Adolescent Medicine
Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research K channel therapeutics at the bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research Microencapsulated cell tracking
Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Cardiovascular risk factors and events in women with androgen excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase
A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
research Clinical Case Notes. Retinoblastoma, microphthalmia and the chromosome 13q deletion syndrome
The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.
research Clinical Case Notes. Optical coherence tomography of adult-onset foveomacular vitelliform dystrophy
Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.
research Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
research Clinical Case Notes. Lipoid proteinosis: a rare disorder with pathognomonic lid lesions
A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.
research Male Androgenetic Alopecia and Cardiovascular Risk Factors
Men with male pattern baldness are more likely to have heart disease risk factors, so they should get heart screenings early.
research Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
research Ophthalmological Complications of Aesthetic Medicine Procedures: A Narrative Review
Cosmetic procedures can cause serious eye problems, so awareness and safety are crucial.
research American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Hyperandrogenic Disorders
The guidelines help doctors diagnose and treat hormone-related disorders in women.
research Association of severity of menstrual dysfunction with cardiometabolic risk markers among women with polycystic ovary syndrome
Severe menstrual issues in PCOS women signal higher risk for heart and metabolic problems.
research Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study
Stem cells can move to brain injury sites and be tracked, showing promise for treating brain diseases.
research Evidence-based consensus on the clinical application of photobiomodulation
Photobiomodulation is safe and effective for treating certain conditions like nerve pain and hair loss.
research Recent advances in the role of neuroregulation in skin wound healing
Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
research Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland
Natural products may help treat skin inflammation from abnormal adrenal hormones.
research Physiopathology of polycystic ovary syndrome in endocrinology, metabolism and inflammation
PCOS involves hormonal imbalance, cysts, and ovulation issues, affecting health and increasing disease risks.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Androgenetic alopecia as an early marker for hypertension
Men with androgenetic alopecia may have higher blood pressure, suggesting early screening for hypertension.
research Androgenetic alopecia and metabolic syndrome: A cross-sectional study in Northeast India
Androgenetic alopecia may predict metabolic syndrome, so routine screening is recommended to prevent cardiovascular issues.