23 citations
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January 1981 Hair is mostly made of three protein types: helical, high-sulfur, and high-tyrosine.
17 citations
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February 1987 in “Journal of the American Academy of Dermatology” The hair cuticle acts as a barrier against fungal infection, which occurs only deep within the hair follicle.
January 2024 in “Doria (University of Helsinki)” Keratins help GLUT2 stay on the cell membrane in pancreatic β-cells.
January 2008 in “Medical Entomology and Zoology” 14 citations
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May 2009 in “Journal of the American Academy of Dermatology” The patient's scalp lesions stabilized with a combination of treatments after initial therapies failed.
24 citations
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July 2014 in “Journal of Investigative Dermatology” Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
2 citations
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November 1996 in “PubMed” Most people have similar hair protein patterns, but a rare variant was found in two women.
7 citations
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March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
2 citations
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August 2013 in “British Journal of Dermatology” Chemotherapy improved a girl's painful foot condition linked to pachyonychia congenita.
2 citations
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July 2001 in “Dermatologic Surgery” Trichoblastic carcinoma may be a distinct type of skin cancer different from basal cell carcinoma.
76 citations
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December 2011 in “Journal of Cell Science” Different keratin types have unique amino acid patterns that are evolutionarily conserved.
1 citations
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March 2019 in “Dermatology Reports” Dermoscopy can help diagnose tinea capitis but should be used with other tests.
Pseudopelade is likely an independent disease due to its distinct features.
27 citations
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April 2004 in “Biochemical and Biophysical Research Communications” Two new gene clusters important for hair formation were found on human chromosome 11.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.
2 citations
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March 1977 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Defective mink guard hairs have split tips and missing cuticle cells, causing a metallic sheen.
1 citations
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May 2016 in “Aktuelle Dermatologie” Trichoscopy helps monitor inflammation in Lichen planopilaris.
December 2020 in “Pathology” A man's skin condition and poor diet led to a scurvy diagnosis.
3 citations
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May 1991 in “Journal of Investigative Dermatology” 38 citations
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January 2014 in “Journal of Dermatological Science” Krtap11-1 is important for hair strength and structure.
86 citations
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May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
118 citations
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January 2013 in “Biomaterials” Keratin from human hair shows promise for medical uses like wound healing and tissue engineering.
July 2019 in “Indian dermatology online journal” Alopecia areata can show unusual red-dotted vessels and dithranol treatment may mask typical patterns.
February 1999 in “The anatomical record” Two mouse mutants have defective hair cuticle cross-linking.
1 citations
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September 2015 in “Serbian Journal of Dermatology and Venereology/Serbian Journal of Dermatology and Venerology” A 19-year-old male had two rare skin conditions causing scarring and permanent hair loss.
Pangolin scales evolved for protection, hardening with age, due to keratin gene diversification.
1 citations
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April 2010 in “Expert Review of Dermatology” The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
7 citations
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March 2003 in “PubMed” The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
1 citations
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January 2012 in “Juntendō Igaku/Juntendo igaku” A simple classification based on symptoms helps diagnose and treat inherited skin disorders in Japan.
June 2017 in “Journal of the American Academy of Dermatology” Plucked hair can help diagnose pemphigus vulgaris early.