13 citations
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August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
December 2023 in “International Journal of Pharmaceutics” New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.
July 2024 in “Journal of Investigative Dermatology” PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study focused on formulating and evaluating a multipurpose herbal liquid shampoo using natural ingredients like Horse Gram, Amla, Fenugreek, Hibiscus, and Flaxseed extracts, known for their cleansing, nourishing, conditioning, anti-dandruff, and hair growth-promoting properties. The shampoo, adjusted to a pH of 5 for scalp compatibility, exhibited a brownish color, pleasant odor, and slightly thick texture. It demonstrated medium foam formation, effective cleansing action, and left hair feeling soft. The formulation, with a 20.8% solid content, showed no signs of skin irritation, confirming its safety for topical use.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study focused on formulating and evaluating a multipurpose herbal liquid shampoo using natural ingredients like Horse Gram, Amla, Fenugreek, Hibiscus, and Flaxseed extracts, known for their cleansing, nourishing, conditioning, anti-dandruff, and hair growth-promoting properties. The shampoo, adjusted to a pH of 5 for scalp compatibility, exhibited a brownish color, pleasant odor, and slightly thick texture. It demonstrated medium foam formation, effective cleansing action, and left hair feeling soft. The formulation, with a 20.8% solid content, showed no signs of skin irritation, confirming its safety for topical use.
7 citations
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October 2019 in “Frontiers in bioengineering and biotechnology” Fusion proteins can protect hair from heat damage.
7 citations
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February 1998 in “Polymer journal” Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
August 2019 in “Journal of The American Academy of Dermatology” Bleach baths with 0.005% hypochlorite help manage atopic dermatitis by affecting skin cells and reducing itchiness.
January 2021 in “Lecture notes in mechanical engineering” High temperatures, acidic conditions, and too much coconut oil damage hair, while a pH of 5 to 7 keeps it healthy.
The 7.5% talok and 2% pare leaf extract hair tonic effectively promotes hair growth, similar to minoxidil.
December 2022 in “Proceeding Bengkulu International Conference on Health” Celery extract hair gel at 5% concentration is best for making hair gel.
A hair tonic with 7.5% daun talok and 2% daun pare promotes hair growth as effectively as minoxidil.
November 2024 in “International Journal of Cosmetic Science” Haircare products with a pH between 5 and 7 are best for maintaining healthy hair.
13 citations
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September 2020 in “Sensors” Hair follicles have a pH gradient, increasing towards the root.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” Green tea leaf extract at 7.5% concentration effectively promotes hair growth, similar to minoxidil.
35 citations
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September 1972 in “Journal of Biological Chemistry” Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
9 citations
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January 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
65 citations
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October 2015 in “Acta Biomaterialia” The nano-carrier makes etoposide safer and more effective against lung cancer.
3 citations
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June 2019 in “Journal of cosmetic dermatology” Lower pH straighteners change hair more but weaken it.
29 citations
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April 2017 in “Macromolecular bioscience” Scientists created tiny pH-sensing gels that can safely measure the pH levels inside hair follicles.
12 citations
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
6 citations
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July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.
193 citations
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August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
12 citations
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February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
February 2024 in “Trends in Sciences” Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
4 citations
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January 2016 in “Journal of analytical & bioanalytical techniques” The herbal hair gel could be a safe hair growth treatment with minimal side effects.
8 citations
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March 2011 in “Endocrine” A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.