May 2026 in “Frontiers in Reproductive Health” This narrative review emphasizes the importance of integrating evidence-based lifestyle and adjunct therapies for managing polycystic ovary syndrome (PCOS), a disorder affecting 6%-13% of reproductive-aged women. It highlights the potential benefits of dietary interventions, such as Mediterranean and low-glycemic index diets, and structured physical activities like aerobic and resistance training, in improving metabolic and hormonal outcomes. Adjunct strategies, including nutraceuticals and phytochemicals, may modulate insulin signaling and inflammation, while psychological interventions can enhance treatment adherence. Complementary systems like Ayurveda and Traditional Chinese Medicine are also explored. The review concludes that a balanced, individualized approach combining lifestyle strategies, pharmacological therapies, and adjunct interventions is essential for effective PCOS management, though further high-quality clinical trials are needed to validate these strategies.
January 2026 in “Journal of Education Health and Sport” Letrozole with lifestyle changes improves fertility in women with PCOS.
March 2025 in “Journal of Neonatal Surgery” Nardostachys Jatamansi is an endangered plant with valuable medicinal properties that could lead to safer drug alternatives.
January 2025 in “FASKES Jurnal Farmasi Kesehatan dan Sains” Erythrina subumbrans leaves may help treat hair loss.
January 2025 in “Open Veterinary Journal” Supplements improved the dog's hair growth without side effects.
Eclipta alba L. (Urang-Aring) can help treat hair loss.
June 2015 in “Obstetrics, gynaecology and reproductive medicine” Hirsutism, excessive hair growth in women, is often caused by polycystic ovarian syndrome and is treated by targeting the cause, lifestyle changes, and medication.
January 2015 in “Indo American Journal of Pharmaceutical Research” Mesotherapy uses small injections to improve skin, reduce fat, and treat hair loss effectively and quickly.
January 2015 in “VetPharma” Alopecia X causes hair loss in young plush-coated dogs and can be treated with various therapies, but hair may regrow and then fall out again.
Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.
18 citations
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January 2020 in “Journal of Clinical Research in Pediatric Endocrinology” The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
9 citations
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November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
October 2016 in “Journal of the Dermatology Nurses’ Association” Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.
1 citations
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July 1976 in “Archives of Dermatology” Some women experienced hair loss after stopping chorionic gonadotropin injections and a low-calorie diet.
8 citations
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April 2019 in “International journal of scientific research in biological science” Tridax procumbens is a widely used medicinal plant with many health benefits.
5 citations
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June 2019 in “British Journal of Dermatology” Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.
January 2022 in “Clinical Cases in Dermatology” A condition called Central Centrifugal Cicatricial Alopecia causes hair loss and scalp burning in middle-aged African women, and it's treated with various medications, hair transplants, and non-drug methods like wigs.
Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
4 citations
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July 2025 in “Frontiers in Pharmacology” Cooling with antioxidants helps protect hair during chemotherapy.
January 2026 in “Frontiers in Pharmacology” Minoxidil can treat hair loss with topical, oral, and sublingual options, offering personalized choices.
August 2025 in “Frontiers in Pharmacology” Periplaneta americana extract helps hair regrowth by reducing inflammation and improving skin bacteria balance.
May 2025 in “Frontiers in Pharmacology” Targeting gut microbiome and metabolome may help treat autoimmune skin diseases like alopecia areata.
January 2026 in “Frontiers in Pharmacology” Anwuligan may help treat hair loss by promoting hair growth.
3 citations
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May 2025 in “Frontiers in Pharmacology” Vismodegib can cause muscle spasms, taste changes, hair loss, fatigue, weight loss, and possibly new issues like skin cancer, dehydration, and swallowing problems, needing close monitoring.
May 2026 in “Frontiers in Pharmacology” Long-term use of 5α-reductase inhibitors may improve survival in men with kidney cancer.
July 2025 in “Frontiers in Pharmacology” G-1 promotes hair growth in female mice by activating specific signaling pathways.
27 citations
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March 2024 in “Frontiers in Pharmacology” Natural products can help overcome cancer drug resistance.
4 citations
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January 2025 in “Frontiers in Pharmacology” Multiomics helps understand and improve skin healing and repair.
2 citations
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September 2025 in “Frontiers in Pharmacology” Empagliflozin helps heal diabetic wounds in rats by reducing inflammation and oxidative stress.