research Clinical Considerations of Bioequivalence for Topical Dermatologic Drugs
Current methods for assessing bioequivalence of topical drugs are limited and lack standardization.
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research Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells
α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Lipid-based nanoformulation optimization for achieving cutaneous targeting: Niosomes as the potential candidates to fulfill this aim
Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
research The Binding of Small Molecules and Polymers to Keratin and Their Effects on the Physicochemical and Surface Properties of Hair Fibers
Certain small molecules and polymers can change hair's physical properties and how it feels by affecting the bonds within the hair.
research Breaking the “rule-of-five” to access Bridged Bicyclic Heteroaromatic Bioisosteres
A new method creates valuable compounds for drug discovery by breaking traditional chemical rules.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Faculty Opinions recommendation of Identification of novel hair-growth inducers by means of connectivity mapping.
Fluphenazine and iloprost can induce hair growth.
research Factors influencing hydrocortisone permeation into human hair follicles: Use of the skin sandwich system
Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Farmácia Avenida - Guimarães e nos Serviços Farmacêuticos da Unidade Local de Saúde do Alto Ave, EPE - Guimarães
Pharmacists play a crucial role in personalized therapy, health literacy, and patient care across various health conditions.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a μ-opiate receptor agonist
Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.
research HPLC characterization, molecular docking, QSAR and molecular dynamics simulation of Alstonia boonei phytochemical analogs as potent 5-alpha reductase inhibitors
Alstonia boonei phytochemicals show promise as alternative treatments for BPH with fewer side effects than current drugs.
research Exploring the Medication Pattern of Externally Used Traditional Chinese Medicine Compound for Hair Loss in the National Patent Database Based on R Language Data Mining
Traditional Chinese medicine for hair loss focuses on "tonifying and activating blood, nourishing the liver and kidney."
research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands#
The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
research Legal issues concerning the promotion of pharmaceutical products on the internet to consumers.
In 1996, promoting drugs online was new and legally unclear.
research The role of hair follicles in the percutaneous absorption of caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
research Anais do V International Workshop on Rational Use of Medicines.
The workshop promoted better medicine use and health practices through global collaboration.
research Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity
Plasmalogens activate a channel in cells that may stimulate hair growth.
research Getting under the skin: what is the potential of the transfollicular route in drug delivery?
The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
research An open-access data set of pig skin anatomy and physiology for modelling purposes
The data set helps improve predictions of how substances are absorbed through pig skin.
research Modulating metal-organic frameworks by surface engineering of stearic acid modification for follicular drug delivery and enhanced hair growth promotion
Modified frameworks with stearic acid enhance drug delivery and promote hair growth.
research FOLLICULAR LIPOSOMAL DELIVERY SYSTEMS
New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
research Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 Inhibitors from Relevant Ethno-pharmacological Plants via In Silico Techniques
Three natural compounds from Ghanaian plants may help treat BPH and alopecia.
research Repurposing FDA approved drugs for psoriasis indications through integrated molecular docking, one-SVM algorithm, and molecular dynamics simulation approaches
Pioglitazone, Trimipramine, and Dimetindene may be repurposed to treat psoriasis.
research Recent Trends and Future Prospects of Phytosomes: A Concise Review
Phytosomes improve the body's absorption of plant extracts for better health benefits.