November 2025 in “BMC Genomics” Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
New methods efficiently isolate dermal papilla cells from hair follicles, preserving their characteristics better than traditional methods.
April 2013 in “Developmental Cell” Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
38 citations
,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
86 citations
,
June 1998 in “Journal of Investigative Dermatology” The hairless gene mutation causes baldness by disrupting hair follicle structure.
53 citations
,
January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
48 citations
,
February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
30 citations
,
November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
29 citations
,
January 2021 in “G3 Genes Genomes Genetics” A 195 bp duplication in the HOXC10 gene causes crests in domestic chickens.
26 citations
,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
23 citations
,
May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
21 citations
,
November 2015 in “Phytomedicine” Glycyrrhizic acid may help reduce unwanted hair growth.
19 citations
,
January 2021 in “Experimental dermatology” Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.
15 citations
,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
15 citations
,
June 2015 in “Human Cell” Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
11 citations
,
June 2012 in “Journal of Dermatological Science” Scientists identified a group of human skin cells with high growth and regeneration potential.
11 citations
,
October 2007 in “Journal of Investigative Dermatology” Mutations in the Sgk3 gene cause fuzzy hair in mice.
10 citations
,
January 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
9 citations
,
April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
9 citations
,
May 2010 in “Journal of Investigative Dermatology” Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.
7 citations
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August 2019 in “Endokrynologia Polska” The free androgen index varies among women with different types of PCOS.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
April 2021 in “Journal of Investigative Dermatology” The research found genes that may protect certain scalp cells from hair loss.
August 2019 in “Journal of Investigative Dermatology” Skin may help in getting rid of excess iron through the process of skin cell renewal.
May 2018 in “Cell stem cell” Myoepithelial cells can repair airways after severe injury.
September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
July 2017 in “Biology bulletin/Biology bulletin of the Russian Academy of Sciences” Specific conditions are needed to keep hair follicle cells effective for hair growth.