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August 2015 in “Molecules” Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.
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April 1979 in “Journal of Ultrastructure Research” February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
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September 2024 in “Animals” Key genes influence melanin in chicken muscles, affecting their value.
December 2025 in “Scientific Reports” α-Mangostin can naturally lighten skin by reducing melanin.
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
August 2025 in “Annals of Medicine” Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
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January 1995 Melanin in black hair protects it from sun damage better than light-brown hair.
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July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
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January 2017 in “Korean Journal of Physiology and Pharmacology” Pimecrolimus boosts melanin production and movement of skin pigment cells.
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June 2024 in “Animals” Genes like MC1R, TYR, MITF, ASIP, and KIT determine horse and donkey coat colors and affect breeding and health.
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January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
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January 1980 in “Journal of Investigative Dermatology”
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January 2002 Melanin and melanocytes contribute to the brown pigmentation in stasis dermatitis.
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July 2002 in “Archives of Pathology & Laboratory Medicine” Tyrosinase and gp100 proteins can help diagnose and treat melanoma.
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
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June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
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November 2022 in “Animals” The research found specific genes and pathways that control fur development and color in young American minks.
April 2026 in “The FASEB Journal” Exosomal miR-199a-3p from dermal papilla cells helps control hair color by affecting melanocytes.
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August 2019 in “Biological & Pharmaceutical Bulletin” Certain flavonoids help grow back colored hair after skin injury.
March 2026 in “Indian Dermatology Online Journal” Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.
March 2009 in “Chinese Journal of Dermatology” Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
November 2022 in “Skin Appendage Disorders” PT-20 did not significantly improve gray hair repigmentation.
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December 2019 in “International Journal of Cosmetic Science” White hair has weaker tryptophan fluorescence than other unpigmented fibers, possibly due to UV exposure or unknown substances.
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
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February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.