research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
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research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes
Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
research Circadian clocks: from stem cells to tissue homeostasis and regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Olfactory receptor OR2AT4 regulates human hair growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research The Peripheral Clock Regulates Human Pigmentation
Certain genes control the color of human hair by affecting pigment production.
research Hair growth promoting effects of adipose tissue-derived stem cells
Fat tissue stem cells may help increase hair growth.
research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases
White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
research Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Clinical and biological impact of the exposome on the skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathway
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research Molecular basis of hair cell loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Lamins in development, tissue maintenance and stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Coffee Silverskin: A Review on Potential Cosmetic Applications
Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
research Nutritional and therapeutic importance of Daucus carota- A review
Carrots are nutritious and offer many health benefits, including antioxidant and anti-inflammatory effects.
research A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition
Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
research Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Scoping Review on the Use of Drugs Targeting JAK/STAT Pathway in Atopic Dermatitis, Vitiligo, and Alopecia Areata
Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
research Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2
Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
research Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
research JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing
JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.