research Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis
Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
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research Col4a2-eGFPmouse model reveals the molecular and functional dynamics of basement membrane remodelling in hair follicle morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research Immunofluorescent localization of collagen types I, III and IV, fibronectin, laminin, and basement membrane proteoglycan in developing mouse skin
research Phototherapy for alopecia areata
Phototherapy can help treat hair loss in alopecia areata.
research Photobiomodulation therapy and 5% minoxidil in female pattern hair loss: a case series focusing on hair growth phases over a shorter timeframe
Combining red laser therapy with minoxidil improves hair growth more effectively than minoxidil alone in women with hair loss.
research 1422 Uncoupling desmosomal cadherin adhesion activates quiescent hair follicle stem cells and orchestrates self-organized regeneration through outside-in signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
research Hierarchical patterning modes orchestrate hair follicle morphogenesis
Hair follicle patterns form through a mix of self-organization and signaling interactions.
research Recent advances in highly-efficient near infrared OLED emitters
New near-infrared OLED emitters are more efficient, especially platinum(II) complexes, and have promising applications like hair growth treatment.
research Hypotrichosis with juvenile macular dystrophy: a case report with molecular study
A new genetic mutation was found causing hair and eye issues in a boy.
research Characterization of novel TMEM173 mutation with additive IFIH1 risk allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Transgenic mice overexpressing CD109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing
Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Reducing PIEZO1 speeds up wound healing.
research Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene
The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.
research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle
research Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury
Vitamin D receptor is essential for proper skin healing after injury.
research Redox-directed interventions targeting skin photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research Abstract 4385: Live-imaging the interface between homeostasis and cancer initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Spectrum of Phenotypes Associated with Human MC1R Variations
MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.
research Ichthyosis follicularis with alopecia and photophobia (IFAP): late diagnosis in 18‐year‐old man
An 18-year-old man was diagnosed with a rare genetic disorder causing hair loss, severe light sensitivity, and skin issues.
research 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
research The effects of infrared radiation on the human skin
Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.
research Melatonin promotes hair regeneration by modulating the Wnt/β ‐catenin signalling pathway
Melatonin helps hair grow by activating a specific signaling pathway.
research Identification of ultraviolet B radiation-induced microRNAs in normal human dermal papilla cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research Epidermis reconstructed from the outer root sheath of human hair follicle on de-epidermized dermis. Effect of retinoic acid
research Application of phototherapy in alopecia
Phototherapy can improve various types of hair loss with minimal side effects, but more research is needed to optimize treatment.
research A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy
Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
research When the Circadian Clock Meets the Melanin Pigmentary System
Silencing certain circadian clock genes increases skin pigmentation.
research 746 Transcriptomic profiling of frontal and occipital dermal papilla reveals potential role of TRPS1 in androgenic alopecia
TRPS1 loss in balding scalp areas contributes to hair loss in androgenic alopecia.
research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire
Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1
A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.