research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
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research Nanofiber-mediated sequential photothermal antibacteria and macrophage polarization for healing MRSA-infected diabetic wounds
The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.
research The role of metabolism in cellular quiescence
Understanding metabolic changes in dormant cells can help treat cancer.
research Prevalence and characteristics of polycystic ovary syndrome in Brazilian women: protocol for a nation-wide case–control study
PCOS is common in Brazilian women and linked to metabolic and reproductive issues.
research Mitochondrial DNA Damage, Oxidative Stress, and Atherosclerosis
Improving mitochondrial health may better treat atherosclerosis than antioxidants.
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research The Role of PGC-1α in Aging Skin Barrier Function
PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
research Triglycerides, independent of Ferriman Gallwey Score, is a main determinant of free testosterone index in PCOS
High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
research Platelet-Rich Plasma (PRP) in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications
Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
research Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats
MicroRNAs and AI can improve cashmere goat hair quality and aid in hair disorder diagnosis.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Quercetin Promotes Production of Secondary Hair Follicle Stem Cells in Cashmere Goat: A Mechanistic Study
Quercetin can boost hair follicle stem cell growth in cashmere goats, potentially improving cashmere quality.
research Hair Follicles as Micro-Organs: MicroRNA-Mediated Control of Growth, Cycling, and Fiber Traits
MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.
research Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling
Rebamipide may help regrow hair by activating hair follicle stem cells.
research Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
research Editor's evaluation: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
research The use of NDYAG laser combined with pulsed light in the treatment of rosacea
Combining NdYag laser with pulsed light effectively treats rosacea with manageable side effects.
research Morphea: progress to date and the road ahead
More research is needed to understand and treat morphea effectively.
research Combined drug triads for synergic neuroprotection in retinal degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Dermal Fibrosis and the Current Scope of Hydrogel Strategies for Scarless Wound Healing
Hydrogels show promise for scarless wound healing by reducing skin fibrosis.
research Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives
Excimer laser therapy can be an alternative for treating superficial morphea when topical steroids don't work.
research Molecular basis of androgen insensitivity
Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
research A 3R (remove-remodel-repair)-Integrated Self-Assembled Chlorella-Gelatin-PEG Hydrogel for Diabetic Wound Healing
CPGel hydrogel heals diabetic wounds effectively in 21 days.
research Cosmétologie de la peau noire
Black skin requires specific cosmetic practices, which can sometimes cause skin issues due to product misuse, and there's a need for better regulations in sub-Saharan Africa.
research Delivery of nanocarriers with dissolvable microneedles for skin treatments: Approaches and challenges
Dissolvable microneedles are a promising, painless method for effective skin treatments.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Dynamic expression of Runx1 in skin affects hair structure
Runx1 is crucial for proper hair structure and development.
research Effects of microenvironment and biological behavior on the paracrine function of stem cells
Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.