research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
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research Addisonian crisis in a young man with atypical anorexia nervosa
A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging
Curcumin may help reverse aging by targeting specific genes.
research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
research An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles
The microneedle patch helps heal infected wounds quickly and without scars.
research Increased hair polyamine levels in patients with alzheimer's disease
Alzheimer's patients have higher levels of certain chemicals in their hair.
research Herbal Treatment for Dermatologic Disorders
Some herbal treatments are effective for skin disorders, but more research and regulation are needed.
research Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician, and the pharmaceutical companies
The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
research Nutraceuticals for Healthy Skin Aging
Certain nutrients can help keep skin healthy as we age.
research Metabolism and skin diseases
Skin health and diseases are closely linked to metabolic processes.
research Effects of the biomimetic peptide Sh-Polypeptide 9 (CG-VEGF) on cocultures of human hair follicle dermal papilla cells and microvascular endothelial cells
Sh-Polypeptide 9 may be better than minoxidil for hair growth and protection against damage.
research Drug safety evaluation of exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research iTRAQ-based proteome profiling revealed the role of Phytochrome A in regulating primary metabolism in tomato seedling
Phytochrome A is crucial for normal metabolism and development in tomato seedlings under far-red light.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue
Caspase-7 has functions in skin and hair that are not related to cell death.
research Skin eruptions specific to pregnancy: an overview
Pregnancy can cause unique skin issues, some of which may risk the mother and baby's health and need careful treatment.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Antiandrogenic therapy with ciproterone acetate in female patients who suffer from both androgenetic alopecia and acne vulgaris
Ciproterone acetate improves hair regrowth and acne in most female patients.
research Intestinal Stem Cell Imaging in Colorectal Cancer Screening
Imaging intestinal stem cells might help detect early signs of colorectal cancer.
research Hair aging and anti-aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
research Dermal macrophage and its potential in inducing hair follicle regeneration
Dermal macrophages might help regrow hair.
research Beneficial effects of zinc on reducing severity of depression
Zinc helps reduce the severity of depression.
research Autoimmune Skin Disorders
The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
research Menopause and Common Dermatoses: A Systematic Review
Menopause influences skin conditions, and hormone therapy should be considered in treatment.
research Cysteine and Glutamine level in hair shaft fractures patients
Cysteine strengthens hair, and glutamine fuels hair growth.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Micro-Injury Induces Hair Regeneration and Vitiligo Repigmentation Through Wnt/ β-Catenin Pathway
Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.
research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evo-Devo
Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.