48 citations
,
March 1997 in “Seminars in Cutaneous Medicine and Surgery” Vitiligo causes white skin patches but can be treated in many ways.
May 2026 in “International Journal of Drug Delivery Technology” Accurate diagnosis of EFFC is crucial for effective counseling and cosmetic care.
June 2025 in “Australasian Journal of Dermatology” Pigmented rings with central clearing help diagnose melasma more accurately.
18 citations
,
April 1989 in “Archives of Dermatology” Iron deficiency can cause hair color changes, which can be reversed with iron supplements.
March 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Facial hyperpigmentation improved with oral isotretinoin and ivermectin cream after Demodex mites were identified as the cause.
5 citations
,
August 2015 in “Sultan Qaboos University medical journal” Vitamin B12 deficiency can cause skin darkening and other symptoms, which improve with B12 supplements.
1 citations
,
April 2015 in “Neurology” Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.
77 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
17 citations
,
December 2013 in “Dermatologic Surgery” The treatment improved hair color in most vitiligo patients without major side effects.
1 citations
,
June 2011 in “InTech eBooks” Darker skin provides more protection against UV damage and cancer.
December 2018 in “European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology” Segmental vitiligo affects hair follicle melanocytes, causing small, uniform depigmented spots.
January 2022 in “Indian dermatology online journal” Pigmented papules on the ear can be a rare skin condition called cutaneous amyloidosis, treatable with topical tretinoin.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
21 citations
,
January 2007 in “Journal of the European Academy of Dermatology and Venereology” Travoprost can help eyelash growth but may cause darkening around the eyes.
9 citations
,
June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
Surgical repigmentation can permanently restore color to white hair in vitiligo patients.
15 citations
,
December 2016 in “Obstetrics & Gynecology” Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.
60 citations
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
April 2023 in “International journal of dermatology and venereology” Dermoscopic features can help identify and differentiate types of pityriasis versicolor.
June 2023 in “International Journal of Dermatology” Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.
19 citations
,
November 2021 in “Lupus Science & Medicine” Black patients with discoid lupus erythematosus have more severe skin damage and higher chances of dyspigmentation, scalp, and ear involvement.
16 citations
,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
12 citations
,
January 2021 in “Dermatology Research and Practice” The 1927 nm Thulium laser effectively and safely treats postinflammatory hyperpigmentation in darker skin tones.
9 citations
,
September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
2 citations
,
September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
Acitretin treatment unexpectedly darkened a patient's gray hair.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
November 2025 in “International Journal of Advanced Research” Platelet-rich plasma therapy effectively treated laser-induced skin lightening.