4 citations
,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
1 citations
,
September 2024 in “Cosmetics” Permanent makeup fades over time and needs reapplication.
October 2025 in “Bioactive Materials” Combining traditional Chinese medicine with microneedles shows promise for effectively treating skin diseases with fewer side effects.
353 citations
,
November 2014 in “Molecular immunology” Porcine skin is very similar to human skin, making it a useful model for research.
48 citations
,
January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
October 2025 in “Advanced Healthcare Materials” Stevioside-based microneedles improve minoxidil delivery and hair growth for treating hair loss.
July 2024 in “International Journal of Molecular Sciences” RF-based therapies might help treat hair loss.
19 citations
,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
June 2025 in “Animal Bioscience” miRNA-24 affects goat coat color by controlling proteins involved in pigment production.
91 citations
,
March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
81 citations
,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
29 citations
,
January 2013 in “International Journal of Medical Sciences” Wnt10b helps hair follicle cells mature and produce pigment.
7 citations
,
February 2019 in “International Journal of Dermatology” Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
November 2025 in “EXPERIMENTAL ANIMALS” Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.
28 citations
,
December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
450 citations
,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
9 citations
,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
3 citations
,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
60 citations
,
April 2006 in “International Journal of Dermatology” Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
11 citations
,
September 2024 in “Journal of the European Academy of Dermatology and Venereology” Hair regrows faster in alopecia areata than skin re-pigments in vitiligo due to differences in stem cells and treatment effects.
8 citations
,
January 2017 in “Korean Journal of Physiology and Pharmacology” Pimecrolimus boosts melanin production and movement of skin pigment cells.
1 citations
,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
1 citations
,
January 2025 in “Regenerative Biomaterials” Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.