January 2026 in “Dermatology Practical & Conceptual” Exosomes can improve skin elasticity, reduce wrinkles, and enhance hydration, but more research is needed.
October 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” Variegated coat color in cats is linked to the Silver locus.
June 2024 in “Research Square (Research Square)” Increased cell death and reduced cell growth in hair follicles contribute to baldness.
March 2024 in “International journal of pharmaceutical sciences and drug research” Androgenetic alopecia is influenced by various factors and can be treated with medications, procedures, and non-drug methods.
November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
February 2008 in “Experimental dermatology” Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
58 citations
,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
24 citations
,
May 2012 in “International Journal of Dermatology” The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
19 citations
,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
15 citations
,
May 2017 in “Lasers in Medical Science” Low-level laser treatment helps mice grow hair by increasing certain protein levels linked to hair growth.
7 citations
,
December 2013 in “The Journal of Dermatology” A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
September 2023 in “Curēus” A 21-year-old male has a benign skin condition called Becker's nevus, which he chose not to treat.
6 citations
,
June 2018 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.
81 citations
,
February 2019 in “Experimental & Molecular Medicine” PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.
November 2025 in “Frontiers in Veterinary Science” A 1.0% tyrosine diet increases melanin in chicken feathers.
340 citations
,
September 2014 in “PLOS Genetics” The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.
195 citations
,
May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
187 citations
,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
159 citations
,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
106 citations
,
June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
84 citations
,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
77 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
72 citations
,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
71 citations
,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
67 citations
,
November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
58 citations
,
June 2018 in “Scientific reports” Researchers found 15 new genetic links to skin traits in Japanese women.
53 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
50 citations
,
April 2014 in “Nature Communications” The research identified new skin traits in mice, some linked to human skin conditions.