research A cell-based system for screening hair growth-promoting agents
Apigenin may help promote hair growth and could treat hair loss.
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research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases
Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
research Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor
Curcumin, EGCG, barringtozenol, and finasteride are effective VEGFR inhibitors.
research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
research Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos
Akt2 protein is essential for normal cell division in early mouse embryos.
research Melatonin Receptors and Their Role in Human Diseases
Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
research ERK1/2 Pathway Is Involved in the Enhancement of Fatty Acids from Phaeodactylum tricornutum Extract (PTE) on Hair Follicle Cell Proliferation
Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
research Sexual dimorphism of COVID-19 inspires drug repositioning and host-targeting immunotherapy for viral pneumonia
Balancing testosterone may reduce COVID-19 severity.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Topical sodium valproate-loaded nanospanlastics versus conventional topical steroid therapy in alopecia areata: a randomized controlled study
Both treatments for alopecia areata showed similar modest effectiveness.
research Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro
Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system
Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
research Progress in Relevant Growth Factors Promoting the Growth of Hair Follicle
Growth factors are crucial for hair follicle growth and development.
research The Role of ADAM17 in PCOS Pathogenesis: A review Paper
ADAM17 could be a potential target for treating PCOS.
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Thymosin β4 Promotes Dermal Healing
Thymosin β4 helps improve skin healing and reduce scarring.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases?
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
research CD98hc (SLC3A2) regulation of skin homeostasis wanes with age
CD98hc's role in skin health decreases with age.