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AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity

research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity

56 citations , December 2011 in “The Plant Journal”

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

research Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease

12 citations , February 2021 in “Translational Psychiatry”

Researchers found two new genetic variants linked to Alzheimer's disease.

research Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice

14 citations , February 2022 in “The Journal of clinical investigation/The journal of clinical investigation”

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

research sm“FISH”ing for Hedgehog

December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hedgehog signaling controls hair follicle development and can affect skin cancer growth.

research The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites

28 citations , January 2015 in “Journal of Cell Science”

PINCH-1 is crucial for skin cell adhesion and movement, working with EPLIN and ILK.

research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia

28 citations , March 2010 in “British Journal of Dermatology”

Genetic marker rs12558842 strongly linked to male hair loss.

research Trans glutaminase-mediated cross-linking in mammalian epidermis

44 citations , January 1984 in “Molecular and Cellular Biochemistry”

research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features

39 citations , September 2018 in “American Journal of Medical Genetics Part A”

A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.

research NIPAL4 mutation c.527C˃A identified in Romanian patients with autosomal recessive congenital ichthyosis

1 citations , December 2016 in “Revista română de medicină de laborator”

The NIPAL4 mutation c.527C>A is common in Romanian patients with autosomal recessive congenital ichthyosis.

research The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

55 citations , November 2010 in “Journal of Allergy and Clinical Immunology”

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

research Phospholipase C‐δ1 is an essential molecule downstream of Foxnl, the gene responsible for the nude mutation, in normal hair development

54 citations , October 2007 in “The FASEB Journal”

Phospholipase C-δ1 is crucial for normal hair development.

research Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization

September 2024

Certain plasma proteins are linked to prostate cancer risk and could help in early detection and treatment.

research Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family

27 citations , June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

research Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

503 citations , May 2009 in “Cell stem cell”

Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.

research Molecular Cloning of 5′ Flanking Region of Ovine Keratin Associated Protein 6-1 Gene and Comparison of the Sequences

January 2007 in “Journal of Inner Mongolia University”

The research helps in creating genetically modified animals to study hair growth.

research The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice

January 2026 in “PLoS Biology”

ARHGEF3 is essential for proper hair follicle development in mice.

research Effect of sterol biosynthesis inhibitors and azole-type inducers on growth and development of Plasmopara viticola on grapevine

7 citations , October 2015 in “Julius Kühn-Institut”

Inhibiting plant sterols reduces grapevine pathogen reproduction.

research MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis

16 citations , April 2021 in “Plant Signaling & Behavior”

MYB30 and EIN3 work against each other to control root hair growth and phosphorus uptake in plants when phosphate is low.

research A gene for monilethrix is closely linked to the type II keratin gene cluster at 12q13

54 citations , January 1995 in “Human Molecular Genetics”

Monilethrix is linked to a gene cluster on chromosome 12.

research The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles

September 2025 in “Science Advances”

PADI4 enzyme slows down cell growth in developing hair follicles.

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Research

research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity

research Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease

research Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice

research sm“FISH”ing for Hedgehog

research The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites

research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia

research Trans glutaminase-mediated cross-linking in mammalian epidermis

research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features

research NIPAL4 mutation c.527C˃A identified in Romanian patients with autosomal recessive congenital ichthyosis

research The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

research Phospholipase C‐δ1 is an essential molecule downstream of Foxnl, the gene responsible for the nude mutation, in normal hair development

research Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization

research Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family

research Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

research Molecular Cloning of 5′ Flanking Region of Ovine Keratin Associated Protein 6-1 Gene and Comparison of the Sequences

research The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice

research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders

research Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia

research Plumbagin, a Natural Compound with Several Biological Effects and Anti-Inflammatory Properties

research Mapping of a novel locus for keratosis follicularis squamosa on chromosome 7p14.3–7p12.1

research Screening of Sheep Fibroblast Cell Line with the Spider Dragline Silk Protein Gene

research Association study reveals a susceptibility locus with male pattern baldness in the Han Chinese population

research Mutation analysis of type II hair keratin gene in a pedigree with monilethrix

research Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa

research CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis

research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

research Effect of sterol biosynthesis inhibitors and azole-type inducers on growth and development of Plasmopara viticola on grapevine

research MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis

research A gene for monilethrix is closely linked to the type II keratin gene cluster at 12q13

research The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles