908 citations
,
July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
854 citations
,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
559 citations
,
October 2020 in “Frontiers in Molecular Biosciences” Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.
517 citations
,
February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
467 citations
,
May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
365 citations
,
March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
323 citations
,
November 2017 in “Bioanalysis” Matrix effects in LC-MS can be managed but not completely avoided.
305 citations
,
December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
287 citations
,
March 1999 in “The Plant Journal” Microtubules help control the direction and stability of root hair growth in Arabidopsis thaliana.
276 citations
,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
245 citations
,
April 2009 in “Circulation Research” CD133+ cells help heal diabetic ulcers by promoting blood vessel growth and activating Wnt signaling.
231 citations
,
October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
229 citations
,
May 2006 in “Journal of Experimental Botany” Reactive oxygen species are essential for plant root hair growth.
211 citations
,
March 2011 in “Journal of Lipid Research” A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
209 citations
,
October 2008 in “The Journal of Pathology” Stem cell niches are essential for tissue health and repair.
200 citations
,
March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
188 citations
,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
170 citations
,
January 2010 in “animal” Hair follicle growth and fiber production in animals are influenced by chemical signals, proteins, pigmentation, genetics, and nutrients.
161 citations
,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
158 citations
,
May 2003 in “Journal of Investigative Dermatology” Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.
150 citations
,
May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
148 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
143 citations
,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
131 citations
,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
124 citations
,
July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
112 citations
,
September 2021 in “BMC Biology” Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.
112 citations
,
January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
111 citations
,
April 2023 in “Ultrasonics Sonochemistry” Ultrasound helps efficiently extract beneficial compounds from maidenhairtree for potential medicinal use.
107 citations
,
April 2014 in “The Plant cell” The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.