research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
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600-630 / 1000+ results research Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics
The method accurately measures finasteride in plasma and is suitable for clinical use.
research Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesisin vivo
Oral zinc sulphate reduces dark hair color in mice.
research 1503 Prostaglandin E2 prevents radiotherapy-induced alopecia by attenuating transit amplifying cell apoptosis through promoting G1 arrest
Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.
research Applications of Trace-Element and Stable-Isotope Geochemistry to Wildlife Issues, Yellowstone National Park and Vicinity
Geochemical methods help manage wildlife by revealing toxic elements and diet details in Yellowstone.
research Dupilumab for prurigo nodularis: real-world outcomes up to 104 weeks from the Dupilumab Italian Prurigo Nodularis (DUPItaPN) study
The Dupilumab Italian Prurigo Nodularis (DUPItaPN) study evaluated the long-term effectiveness and safety of dupilumab in 543 adults with prurigo nodularis (PN) over 104 weeks. The study found that dupilumab significantly improved symptoms, with the mean Worst Itch Numeric Rating Scale (WI-NRS) score decreasing from 8.7 to 1.7, and 86.8% of patients achieving a ≥4-point reduction by week 104. Additionally, 81.2% of patients reached an Investigator Global Assessment for PN-Stage (IGA PN-S) of 0/1. The Dermatology Life Quality Index (DLQI) improved from 17.4 to 2.6. Dupilumab was well tolerated, with only 2.9% discontinuing due to adverse events, and no cancer progression or viral reactivation observed. The study supports dupilumab as a long-term treatment option for moderate-to-severe PN, even in elderly and comorbid patients.
research Rapid determination of finasteride in human plasma by UPLC–MS/MS and its application to clinical pharmacokinetic study
New method measures finasteride in blood quickly and accurately.
research Human Hair Follicle Benzo[a]pyrene and Benzo[a]pyrene 7,8-diol Metabolism: Effect of Exposure to a Coal Tar-Containing Shampoo
Coal tar shampoo increases enzyme activity in hair follicles, enhancing carcinogen binding to DNA.
research Systematically optimized coenzyme q10-loaded novel proniosomal formulation for treatment of photo-induced aging in mice: characterization, biocompatibility studies, biochemical estimations and anti-aging evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research Determination of dichloromethane and chloroform in Finasteride by SPME-GC
The method accurately measures dichloromethane and chloroform in finasteride.
research LB1681 Risk of merkel cell carcinoma progression after treatment discontinuation in patients with an objective response to anti-PD-(L)1 immunotherapy
Longer immunotherapy treatment may improve outcomes for Merkel cell carcinoma patients.
research Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo
Physcion may help treat hair loss by blocking an enzyme linked to baldness.
research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry
The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.
research Female Hair Thinning
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research Determination of traces of silver in human scalp hair slurries by electrothermal atomic absorption spectrometry
research High-dose alpha-tocopherol as a preventive of doxorubicin-induced alopecia.
Alpha-tocopherol does not prevent hair loss from doxorubicin.
research Mitochondrial Oxygen Consumption and Immunocytochemistry of Human Dental Pulp Stem Cell Following 808 nm PBM Therapy: A 3D Cell Culture Study
PBM therapy improves mitochondrial function and promotes tissue regeneration in dental pulp stem cells.
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
research 적하수오 에탄올 추출물의 melanin 합성 촉진효과
PMEE may help reverse greying hair by boosting melanin production.
research Molecular mapping of lymph node metastases by real-time reverse transcription polymerase chain reaction in two melanoma patients
The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
research 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2 /HO ‐1 signalling pathway
4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.
research 306 Effect of Cellular Blood Components on Chemotherapy Induced Alopecia
Mononuclear cells may protect against certain chemotherapy-induced hair loss.
research It's elemental!
Selenium is important for health but must be consumed in the right amount to avoid health issues.
research Identifikasi bakteri Resisten selenium (Se) berdasarkan gen 16s rRNA dari koleksi laboratorium mikrobiologi Universitas Islam Negeri (UIN) Maulana Malik Ibrahim Malang
Four bacteria from the lab were found to be resistant to selenium.
research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
research 412 DETECTION OF CIRCULATING PROSTATE CANCER CELLS BY MEANS OF AN ANTIBODY-CONJUGATED NANOPARTICULAR BIOSENSOR
The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.
research Effect of gamma-ray exposure on the genome-editing efficiency of improved genome-editing via oviductal nucleic acids delivery (i-GONAD)
Gamma-ray exposure improves genome editing efficiency in mice using the i-GONAD method.
research A.S.P.E.N. Parenteral Nutrition Trace Element Product Shortage Considerations
Use oral or enteral nutrition when possible and reserve IV trace elements for those who truly need them.
research Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.