61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
January 2025 in “MEDS Public Health and Preventive Medicine” Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.
8 citations
,
October 2017 in “Dermatology practical & conceptual” A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.
46 citations
,
September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
144 citations
,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
185 citations
,
June 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
34 citations
,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
September 2025 in “Drug Design Development and Therapy” Combining platelet-rich products, biomaterials, and bioactive substances may improve skin treatment, but more research is needed.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
2 citations
,
September 2022 in “Cellular and molecular biology” Agaricus bisporus derived β-Glucan could be an effective cervical cancer treatment with antimicrobial and antioxidant properties.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
14 citations
,
April 2000 in “Animal Science/Animal science” Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
1 citations
,
May 2006 in “Expert Opinion on Therapeutic Patents” No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.
1 citations
,
October 1996 in “Journal of Cutaneous Medicine and Surgery” Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
March 2022 in “Biomedical Journal of Scientific & Technical Research” Improving mitochondrial health may help alleviate symptoms like chronic fatigue and depression.
Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.
5 citations
,
May 1983 in “Australian journal of biological sciences” Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.
64 citations
,
March 2004 in “Journal of Clinical Investigation” Targeting ornithine decarboxylase can help prevent skin cancer.
8 citations
,
August 2014 in “Biochemical and Biophysical Research Communications” ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
5 citations
,
January 2025 in “Pharmaceuticals” Coffea arabica shows promise for skin care due to its beneficial compounds.
December 2022 in “Cosmetics” The food supplement improved hair growth and strength in people with a certain type of hair loss and had no major side effects.
65 citations
,
March 2004 in “Journal of Clinical Investigation” Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
1 citations
,
February 2022 in “Biological Trace Element Research” The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
42 citations
,
February 1996 in “Journal of Investigative Dermatology” Polyamines, especially spermidine, are essential for hair growth.
41 citations
,
March 2017 in “PLoS neglected tropical diseases” Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.
14 citations
,
January 2001 in “Clinical chemistry” Hair can be used to measure cancer-related chemicals noninvasively.
13 citations
,
March 1999 in “Biochemical Journal” Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
12 citations
,
February 2010 in “Tetrahedron Letters” New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
10 citations
,
June 2001 in “Annals of neurology” Alzheimer's patients have higher levels of certain chemicals in their hair.
9 citations
,
April 2006 in “International Journal of Dermatology” DFMO may help control hair growth and treat cancer.