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GlossaryPolymerase Chain Reaction

method to amplify DNA, creating millions of copies quickly

Polymerase Chain Reaction (PCR) is a laboratory technique used to amplify small segments of DNA, making millions of copies from a tiny initial sample. This process is crucial for various applications, including genetic testing, forensic analysis, and diagnosing diseases, as it allows scientists to study DNA in greater detail.

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Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction

research Analysis of Gene Expression in Isolated Single Hair Follicles: An Approach Using Semiquantitative Reverse-Transcriptase—Polymerase Chain Reaction

May 1995 in “Journal of Investigative Dermatology”

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

research Molecular mapping of lymph node metastases by real-time reverse transcription polymerase chain reaction in two melanoma patients

March 2011 in “Journal of Dermatology”

The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.

research Accurate quantification of minimal residual disease at day 15, by real-time quantitative polymerase chain reaction identifies also patients with B-precursor acute lymphoblastic leukemia at high risk for relapse

13 citations , August 2000 in “Blood”

Measuring minimal residual disease on day 15 helps identify high-risk leukemia patients.

research Development of a DNA-analytical Method for the Identification of Animal Hair Fibers in Textiles

46 citations , January 2009 in “Textile Research Journal”

Researchers developed a new method to identify animal hair in textiles, which is effective for various fibers and more reliable than previous methods.

research Detection of human papillomavirus type 56 DNA, belonging to a mucous high-risk group, in hair follicles in the genital area of a woman no longer suffering from viral warts

21 citations , July 2004 in “British Journal of Dermatology”

HPV type 56 can hide in hair follicles even without visible warts.

research Trichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in immunocompromised patients

19 citations , March 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

Trichodysplasia spinulosa is a rare skin disease in immunocompromised patients caused by a specific virus targeting hair follicle cells.

research African Trypanosoma infection in a dog in France

11 citations , May 2011 in “Veterinary Record”

A dog in France died from an African parasite infection after traveling from Senegal.

research Isolation ofStaphylococcus simulansfrom Dermatitis in a Captive African Pygmy Hedgehog

8 citations , June 2011 in “Journal of Zoo and Wildlife Medicine”

Staphylococcus simulans may cause dermatitis in African pygmy hedgehogs.

research Stable transfection and identification of a hair follicle-specific expression vector of IGFBP-5 in goat fetal fibroblasts

6 citations , January 2014 in “Genetics and Molecular Research”

The method successfully created stable transfection donor cells for goat hair follicle research.

research Analysis of DNA in hair fibers.

6 citations , May 2003 in “PubMed”

Small amounts of DNA can be found in the hair shaft, especially near the root, but it decreases with hair treatments and washing.

research A Case of Relapsed Leprosy Successfully Treated With Sparfloxacin

6 citations , November 1996 in “Archives of Dermatology”

A man's relapsed leprosy was successfully treated with the antibiotic sparfloxacin.

research Polymorphism in the A2M gene associated with high-quality milk in Murrah buffaloes (Bubalus bubalis)

5 citations , January 2016 in “Genetics and molecular research”

Certain genetic variations in the A2M gene are linked to better milk quality in Murrah buffaloes.

research Skin-specific transgenic overexpression of ovine β-catenin in mice

2 citations , January 2023 in “Frontiers in Genetics”

Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.

research Syphilis: today

2 citations , October 2010 in “Reviews in Medical Microbiology”

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

research Alopecia Areata is associated with MICA and an extended HLA haplotype

1 citations , March 2004 in “Journal of the American Academy of Dermatology”

Certain genes are linked to the risk of developing Alopecia Areata.

research Clinical pathology in equine dermatology

1 citations , June 2016 in “Equine Veterinary Education”

The document concludes that using the right diagnostic methods and careful sample handling is crucial for accurately diagnosing horse skin diseases.

The Evaluation of IL-4 VNTR Intron 3 and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case–Control Study

research The evaluation of IL-4 VNTR intron 3 and TNF-α (rs1799964) gene polymorphisms in Egyptian patients with alopecia areata: a case–control study

July 2024 in “Egyptian Journal of Medical Human Genetics”

These gene variations are not linked to alopecia areata in Egyptians.

The Evaluation of IL-4 Intron 3 VNTR and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case-Control Study

research The evaluation of IL-4 intron 3 VNTR and TNF-α (rs1799964) gene polymorphisms in Egyptian patients with Alopecia Areata: a case-control study

December 2023 in “Research Square (Research Square)”

These specific gene polymorphisms are not linked to Alopecia Areata in Egyptians.

research Evaluation of androgen receptor gene as a candidate gene in female androgenetic alopecia

March 2009 in “International Journal of Dermatology”

The androgen receptor gene doesn't help identify women likely to have female pattern hair loss.

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

Researchers found WNT10A to be a key gene in developing goat hair follicles.

research Coenzyme Q10 has anti-aging effects on human hair

5 citations , February 2009 in “International Journal of Cosmetic Science”

Coenzyme Q10 helps reduce aging in human hair.

research Clinical picture, diagnosis, treatment and outcome of severe acute respiratory syndrome (SARS) in children

42 citations , November 2004 in “Paediatric Respiratory Reviews”

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

research Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene.

24 citations , July 1994 in “Molecular Endocrinology”

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

research Interferon β Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro

13 citations , January 2002 in “Biochemical and biophysical research communications”

Interferon β from hair cells stops the growth of other hair cells.

EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

research EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes

12 citations , December 2020 in “Archives animal breeding/Archiv für Tierzucht”

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

research Extraction and Detection of mRNA from Horsehair

5 citations , January 2006 in “Journal of veterinary medical science”

RNA can be extracted from horsehair roots for analysis.