86 citations
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November 2015 in “Journal of Gastroenterology” The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.
April 1996 in “Journal of Dermatological Science” 7 citations
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December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” 73 citations
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April 2006 in “BioTechniques” Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.
3 citations
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February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Noncoding dsRNA helps produce exosomes that aid in skin regeneration.
62 citations
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August 2023 in “International Journal of Nanomedicine” Pluronic F127-derived hydrogels show promise for effective wound healing and repair.
2 citations
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September 2024 in “Asian Journal of Pharmaceutics” Niosomes are effective carriers for targeted drug delivery, improving drug stability and efficiency.
January 2019 in “Research & Reviews: Journal of Pharmaceutics and Nanotechnology” Nanotechnology can effectively deliver antimicrobial peptides for treating infections.
September 2025 in “Medical Materials Research” Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
39 citations
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December 1998 in “Journal of Cell Science” The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.
26 citations
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January 1992 in “Carcinogenesis” TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
August 2015 in “MOJ proteomics & bioinformatics” ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
1398 citations
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May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
4 citations
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January 2011 Phenylpropanoid sucrose esters show potential as anticancer agents.
46 citations
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December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
April 2023 in “Journal of Investigative Dermatology” The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
6 citations
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June 2025 in “Nano Biomedicine and Engineering” Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.
40 citations
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January 2017 in “Intestinal Research” Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
January 2019 in “Springer eBooks” PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.
May 2023 in “CRC Press eBooks” Liposomes can improve hair care and treat hair issues effectively.
3 citations
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March 2017 in “Pediatric Dermatology” FOXN1 duplication can cause excessive hair growth.
13 citations
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January 2002 in “Biological chemistry” Different conditions affect how hair proteins assemble, and certain mutations can change their structure.
January 2024 in “Wiadomości Lekarskie” Low-penetration genes might help personalize colorectal cancer prevention.
Ribonucleotide excision repair is crucial to prevent skin cancer.
Nod factor can trigger changes in legume root hairs with just one molecule.
93 citations
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May 2010 in “European Journal of Cancer” BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
March 2026 in “Preprints.org” Platelet-rich plasma, microneedling with minoxidil, and topical finasteride are promising treatments for hair loss.
April 2026 in “Current Opinion in Genetics & Development” This mini-review discusses the role of RNA in cellular plasticity during homeostasis and regeneration, highlighting how endogenous and damage-released RNAs serve as signals that influence cell identity. It examines the function of repetitive-element-derived RNAs and regulatory long-noncoding RNAs (lncRNAs) in modulating stem and progenitor cell plasticity across various systems, including hematopoietic, pluripotent, and muscle systems, by linking stress sensing to cell-fate decisions. Additionally, the review addresses extracellular dsRNA/TLR3 signaling and injury-induced lncRNAs in the regeneration of epithelial, neural, cardiac, and vascular tissues, emphasizing how extracellular RNA affects inflammatory and stromal responses. Overall, RNA is portrayed as a crucial regulator of cellular plasticity in development, tissue maintenance, and regeneration.