research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
A new compound effectively inhibits human 5α-reductase 1.
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research Pharmacological Activity and Clinical Use of PDRN
PDRN helps repair tissue and improve wound healing with a high safety profile.
research Chemical modification of keratin fibers using 2‐iminothiorane hydrochloride
2-iminothiorane hydrochloride improves hair waving permanence without damage.
research Synthesis of 11α-hydroxyprogesterone hartens
Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
research 3D-printed porous functional composite scaffolds with polydopamine decoration for bone regeneration
The scaffold with polydopamine and bioactive glass effectively promotes bone regeneration.
research Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata
The DPCP/HPβCD complex improves solubility and anti-inflammatory effects for alopecia areata treatment.
research Efficacy and safety of non‐cross‐linked hyaluronic acid compound in the treatment of keratosis pilaris: A split‐body randomized clinical trial
The non-cross-linked hyaluronic acid compound effectively and safely improves keratosis pilaris.
research Production and biological activities of oligo pectin from early immature fruit of Durio zibethinus L.
Extracted pectin from immature durian shows potential for use in cosmetics due to its strong antioxidant and protective properties.
research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient
PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
research Cover stories: 10 start-ups to watch: Liquid Light
Pomiferin may improve skin and scalp health by boosting important protein expression.
research Protective effect of conditioning agents on Afro‐ethnic hair chemically treated with thioglycolate‐based straightening emulsion
Conditioning agents, especially jojoba oil and lauryl PEG/PPG-18/18 methicone, protect and strengthen chemically straightened Afro-ethnic hair.
research Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress
Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
research Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.
TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.
research Silicones as conditioning agents in shampoos
Silicones in shampoos make hair smoother, easier to manage, and reduce friction.
research PP405 in Alopecia: An Emerging Molecule worth Investigating
PP405 shows promise as a new, effective treatment for hair loss with minimal side effects.
research Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications
Polyelectrolytes can improve cell surfaces for better medical applications.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Tunable Keratin Hydrogels for Controlled Erosion and Growth Factor Delivery
Keratin hydrogels can be customized for better tissue healing.
research Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes
Geranyl acetate can protect skin cells from damage and inflammation caused by para-phenylenediamine.
research Commentary on Safety of Perfluorodecalin-Infused Silicone Patch in Picosecond Laser-Assisted Tattoo Removal
research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
research Assessment of styling performance in hair gels and hair sprays by means of a new two-point stiffness test.
The new stiffness test works well for gels but not for sprays.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery
PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
research Hypoxia-preconditioned ADSC exosomes encapsulated in a multifunctional dual-network hydrogel promote the healing and functional regeneration of seawater-immersed wounds
The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Safety of a Perfluorodecalin-Infused Silicone Patch in Picosecond Laser-Assisted Tattoo Removal
research Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection
The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
research 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum.
PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.
research Curcumin grafted poly(vinyl alcohol) for ascorbyyl palmitate encapsulation
Encapsulating ascorbyl palmitate in curcumin-grafted particles improves its stability and skin penetration.