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research Generating iPSCs with a High-Efficient, Non-Invasive Method—An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming

3 citations , June 2022 in “Cells”

The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.

research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture

32 citations , September 1996 in “Archives of Dermatological Research”

research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture

6 citations , September 1996 in “Archives of Dermatological Research”

research Expression patterns of hair-related keratins and epithelial keratins in onychopapilloma: The significance of clarifying the origin of onychopapilloma

3 citations , November 2022 in “Frontiers in Medicine”

Onychopapilloma likely originates from the nail bed, not the nail matrix.

Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix

research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix

30 citations , April 2017 in “European Journal of Cell Biology”

CIP/KIP proteins help stop cell division and support hair growth.

research Pre-keratin isolated from epidermal microsomes

7 citations , December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors

research Stem cell quiescence acts as a tumour suppressor in squamous tumours

66 citations , December 2013 in “Nature Cell Biology”

Inactive hair follicle stem cells help prevent skin cancer.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

12 citations , July 2019 in “Veterinary Dermatology”

Nestin-expressing progenitor cells become outer root sheath keratinocytes.

research Keratoacanthoma of the lip: A case report with emphasis on histogenesis

8 citations , January 2017 in “Journal of Oral and Maxillofacial Pathology”

Keratoacanthomas on lips may originate differently than those on skin.

research Cell death by cornification

375 citations , June 2013 in “Biochimica et biophysica acta. Molecular cell research”

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

research Exploiting the Keratin 17 Gene Promoter To Visualize Live Cells in Epithelial Appendages of Mice

58 citations , July 2005 in “Molecular and Cellular Biology”

A specific gene segment can make mouse skin cells glow, helping study hair growth and gene effects.

research Keratins as mediators of glucose sensing in the pancreas

January 2024 in “Doria (University of Helsinki)”

Keratins help GLUT2 stay on the cell membrane in pancreatic β-cells.

research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation

79 citations , August 1998 in “The Journal of Cell Biology”

Keratin 16 delays skin maturation and affects skin and hair development in mice.

research Skin Stem Cells: At the Frontier Between the Laboratory and Clinical Practice. Part 1: Epidermal Stem Cells

2 citations , November 2015 in “Actas Dermo-Sifiliográficas”

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

research Collagen-type synthesis in human-hair papilla cells in culture

28 citations , April 1988 in “Archives of Dermatological Research”

research Merkel cell polyomavirus infection and persistence modelled in skin organoids

2 citations , February 2025

Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

330 citations , December 2009 in “Cell stem cell”

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

research 507 Trial to investigate the role of ATP-sensitive potassium channels (KATPc) in dermal papilla cells (DPCs)

November 2024 in “Journal of Investigative Dermatology”

ATP-sensitive potassium channels are important for hair growth.

research Single cell transcriptomics of human epidermis reveals basal stem cell transition states

5 citations , September 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

Basal stem cells in the skin have distinct types that are crucial for skin structure and health.

research Cornification

September 2018

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

research Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study

27 citations , December 2005 in “Journal of Cutaneous Pathology”

The malignant pilomatricoma showed strong epithelial keratin expression, suggesting it may not calcify.

research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.

35 citations , December 2008 in “PubMed”

Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.

research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1

20 citations , April 2009 in “Cell Biology International”

Hair follicle stem cells can become corneal-like cells with the help of pax6.

research Expression pattern of human hair keratin basic 1 (hHbl) in hair follicle and pilomatricoma

8 citations , April 1997 in “Experimental Dermatology”

hHbl gene is active in hair shaft cells and some pilomatricomas.

research EctopicAtoh1expression drives Merkel cell production in embryonic, postnatal and adult epidermis

41 citations , January 2015 in “Development”

Atoh1 expression can create new Merkel cells in the skin.

research Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis

41 citations , July 1994 in “Journal of Dermatological Science”

Hair follicle cells need complex interactions to fully differentiate.

research Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.

79 citations , June 1993 in “Molecular and Cellular Biology”

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

research Epidermal stem cells in the skin

January 2008 in “Chinese bulletin of Life sciences”

Epidermal stem cells help renew skin and regenerate hair follicles.

research Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2

175 citations , September 1998 in “British Journal of Dermatology”

Keratin 17 gene mutations cause both steatocystoma multiplex and pachyonychia congenita type 2.

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