16 citations
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June 2022 in “Journal of Pediatric Endocrinology and Metabolism” Reducing phthalate exposure may help prevent early puberty in girls.
13 citations
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October 2006 in “Pediatrics in review” Early puberty is more common in girls and African-American children, possibly due to nutrition, obesity, stress, and environmental factors, and is treated with hormone therapy.
3 citations
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July 2015 in “Pediatrics in review” Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.
2 citations
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January 2000 in “Pediatrics in review” Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.
February 2025 in “Medicine” Precocious puberty in girls is linked to cosmetics, pollution, light exposure, early sexual information, diet, and hereditary factors.
January 2025 in “BMJ Case Reports” Precocious puberty can signal familial adenomatous polyposis.
January 2024 in “Frontiers in endocrinology” Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.
November 2022 in “Journal of the Endocrine Society” An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
October 2022 in “Medical Clinical Update Journal” Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.
August 2020 in “Nigerian journal of paediatrics” A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.
34 citations
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May 1987 in “European Journal of Pediatrics” Buserelin safely and effectively suppresses early puberty, potentially improving final height.
January 2026 in “International Journal of Women s Health” A new model helps predict treatment success in girls with early puberty.
October 2023 in “BMC endocrine disorders” A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.
192 citations
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January 1976 in “The Journal of Clinical Endocrinology & Metabolism” Androgen levels increase with puberty and are linked to sexual hair development.
6 citations
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August 2020 in “JCRPE” A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
3 citations
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October 2024 in “Advances in Therapy” Triptorelin effectively treats central precocious puberty in Chinese children with minimal side effects.
3 citations
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September 2020 in “Journal of developmental and behavioral pediatrics/Journal of developmental & behavioral pediatrics” The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.
21 citations
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January 2008 in “Journal of Pediatric Endocrinology and Metabolism” Anastrozole and cyproterone acetate treatment can help increase adult height in boys with testotoxicosis.
April 2025 in “International Journal For Multidisciplinary Research” A rare ovarian tumor caused early puberty in a 3-year-old girl.
October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology” A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
46 citations
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
18 citations
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February 2010 in “Odontology” The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
15 citations
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April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
3 citations
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November 2015 in “Endocrinology, Diabetes & Metabolism Case Reports” Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.
April 2026 in “International Journal of Drug Delivery Technology” Girls in Tamil Nadu typically start menstruating around age 12.84, influenced by lifestyle and family factors.
October 2025 in “Journal of the Endocrine Society” A rare pituitary tumor in an 18-year-old male caused hormonal issues and vision loss, requiring surgery and further treatment.
August 2025 in “Journal of Pediatric Endocrinology and Metabolism” A rare ovarian tumor in a 2-year-old girl was successfully removed, normalizing her hormone levels.
January 2023 in “Pediatric Endocrinology Diabetes and Metabolism” Isolated pubic hair in infants is usually harmless and resolves on its own.
January 2023 in “Pediatrics International” Non-classical 21-hydroxylase deficiency can be missed in newborn screenings and should be considered in cases of early puberty or virilization.