Premature Pubarche During Minipuberty: Literature Review and Two Case Reports

The document reviewed isolated premature pubarche (PP) in infancy, focusing on two male infants with scrotal hair during minipuberty. It concluded that isolated pubic hair in infancy was likely a mild, self-limiting variant of precocious puberty due to increased sensitivity of hair follicles to transiently elevated androgen levels. This condition typically resolved spontaneously without progression of puberty, as demonstrated in the two cases. Hormonal tests showed normal results, and no significant hormonal disorders were found. Monitoring was recommended to exclude serious underlying causes, but intensive diagnosis was often unnecessary unless other signs of puberty were present.