research Location and fine structure of melanocytes in human fetal scalp hair follicles.
Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
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390-420 / 1000+ resultsresearch Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway
BMP signaling affects hair color by interacting with the MC-1R pathway.
research Effects of SLC45A2 and GPNMB on Melanin Deposition Based on Transcriptome Sequencing in Chicken Feather Follicles
SLC45A2 and GPNMB genes help control chicken feather color by promoting melanin.
research Human melanocyte development and melanoma dedifferentiation at single cell resolution
Human melanocytes have unique traits that affect melanoma development and prognosis.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/assets/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
research Skin precancer.
Sun exposure and genetics increase skin cancer risk from precancerous lesions.
research Photobiomodulation for Skin Pigmentation Disorders: A Dual-Function Treatment
Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
research 1339 Casein kinase 1 inhibition in keratinocytes enhances the migration of melanocyte precursors in the hair follicle via KitL/c-Kit signaling pathway
Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice
Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
research Melasma in Men
Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
research Hyperpigmentation and Melasma
Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
research Chemical Leukoderma from Hair Dye Containing para-Phenylenediamine
Hair dye with para-phenylenediamine can cause skin depigmentation.
research An Update on Drug-Induced Pigmentation
Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
research Keratinocyte Cytokine Networks Associated with Human Melanocytic Nevus Development
Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
research Disseminated Nonsegmental Vitiligo Associated With Halo Nevi and Premature Gray Hair
A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
research Lichen planus pigmentosus: a clinico‐pathological study in a Caucasian population from North Africa
Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research 519 Design of a new molecule proven to be safe and effective for topical depigmenting and antiaging method
A new molecule was found to be a safe and effective skin lightener and anti-aging product.
research Premature Greying of Hair (Premature Canities): A Concern for Parent and Child
Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
research Modified phenol peels for treatment‐refractory hyperpigmentation of lichen planus pigmentosus: A retrospective clinico‐dermoscopic analysis
Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.
research The Processed Radish Extract Melanogenesis in Humans and Induces Anti-Photoaging Effects in Ultraviolet B-Induced Hairless Mouse Model
Heated radish extract may help lighten skin and reduce aging signs.
research How the leopard gets its spots: a transmembrane peptidase specifies feline pigmentation patterns
A gene called Taqpep affects cat coat patterns like stripes and blotches.
research Platelet-Rich Plasma in Melasma—A Systematic Review
Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
research In vivo multiphoton microscopy imaging of vitiligo (Conference Presentation)
Multiphoton microscopy helps understand and improve vitiligo treatments by visualizing skin cell changes.
research [Protective effect of melatonin on oxidative stress inducing hair follicle injury in scald rat].
Melatonin may protect rat hair follicles from damage caused by oxidative stress after a burn.
research Pigmentary mosaicism: An update
Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
research Total melanonychia of 20 nails as a rare manifestation of vitamin B12 deficiency
Vitamin B12 deficiency can cause darkening of all nails.
research On the etiology of vitiligo and gray hair
Melanocytes are destroyed by factors needed for melanin production, causing vitiligo and gray hair.