10 citations
,
March 2019 in “Journal of neuroendocrinology” Testosterone affects stress hormone levels differently in adolescent and adult male rats.
2 citations
,
September 2020 Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
3 citations
,
October 2024 in “The Journal of Clinical Endocrinology & Metabolism” Potential androgen excess signs vary by demographics and health, needing inclusive evaluation.
37 citations
,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
May 2026 in “Comprehensive Psychoneuroendocrinology” Hair analysis can effectively assess long-term hormone activity in young children.
April 2025 in “Brazilian Journal of Hair Health” Early exposure to sexualized content and poor lifestyle choices may lead to early hair loss.
January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
50 citations
,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
September 2008 in “Fertility and Sterility” Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
January 2025 in “Biomedicines” High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.
1 citations
,
January 2010 in “uO Research (University of Ottawa)” Atrazine and finasteride disrupt hormone signaling and affect frog development.
11 citations
,
October 2002 in “The Journal of Clinical Endocrinology & Metabolism” Enzyme activities do not cause early pubic hair in these girls.
May 2025 in “Neuropharmacology” Finasteride reduced seizures and prevented cognitive issues in rats after neonatal asphyxia but increased anxiety later.
1 citations
,
March 2025 in “Archivos Argentinos de Pediatria” Exposure to certain chemicals in food and containers may increase the risk of early breast development in young girls.
2 citations
,
June 2018 in “Physiology & behavior” Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
169 citations
,
November 2009 in “The Journal of Clinical Endocrinology & Metabolism” Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.
January 2024 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” Environmental and social factors greatly affect women's reproductive health.
28 citations
,
January 2003 in “Urologic oncology” Suppressing certain hormones might help prevent prostate cancer.
1 citations
,
January 2023 in “Journal of Obstetrics and Gynaecology” High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.
7 citations
,
April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
15 citations
,
June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
19 citations
,
June 2006 in “Physiology & Behavior” Finasteride slows down motherly behavior in first-time pregnant rats.
86 citations
,
February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
November 2022 in “Journal of the Endocrine Society” An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
August 2023 in “Revista Contemporânea” Early life factors, including a mother's health and environment, can affect the chances of developing polycystic ovary syndrome later in life.
67 citations
,
February 1997 in “Teratology” Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
195 citations
,
June 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.