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GlossaryPrincipal Component Analysis

statistical method reducing data dimensions while preserving variance

Principal Component Analysis (PCA) is a statistical technique used to simplify complex datasets by transforming them into a set of new, uncorrelated variables called principal components. These components capture the most significant patterns in the data, making it easier to visualize and analyze, especially in fields like genetics and biology where large datasets are common.

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Application of Phytochemical Screening and a Combined FTIR Spectroscopy and Principal Component Analysis for Effective Discrimination of Two Varieties of Eclipta Alba (L.) Hassk.

research Application of phytochemical screening and a combined FTIR spectroscopy and principal component analysis for effective discrimination of two varieties of Eclipta alba (L.) Hassk.

2 citations , January 2018 in “International Journal of ChemTech Research”

The two Eclipta alba varieties can be distinguished by their chemical differences.

Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds

research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds

6 citations , August 2004 in “Journal of Chemical Information and Computer Sciences”

The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.

Phytochemical Analyses of Ziziphus Jujuba Mill. Var. Spinosa Seed by Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry and Gas Chromatography-Mass Spectrometry

research Phytochemical analyses of Ziziphus jujuba Mill. var. spinosa seed by ultrahigh performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry

38 citations , January 2013 in “Analyst”

The study found that Ziziphus jujuba seeds contain beneficial compounds for treating insomnia and anxiety and that the methods used are effective for assessing their quality.

research Investigation of human hair using ToF-SIMS: From structural analysis to the identification of cosmetic residues

4 citations , April 2018 in “Journal of vacuum science and technology. B, Nanotechnology & microelectronics”

The conclusion is that a new method can identify cosmetic residues on hair and match them to their products.

research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

research Worldwide diversity of hair curliness: a new method of assessment

95 citations , October 2007 in “International Journal of Dermatology”

A new method accurately classifies hair types, showing global hair diversity.

research The Black identity, hair product use, and breast cancer scale

24 citations , December 2019 in “PLoS ONE”

The BHBS is a valid tool to study cultural norms and breast cancer risk in Black women.

research 555 Dermal single-cell atlas: a novel tool to explore fibroblast heterogeneity

November 2022 in “Journal of Investigative Dermatology”

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

research 267 Deep phenotyping of patients with xeroderma pigmentosum and trichothiodystrophy

April 2017 in “Journal of Investigative Dermatology”

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

research A Novel Fusion Technique for Early Detection of Alopecia Areata Using ResNet-50 and CRSHOG

2 citations , January 2024 in “IEEE Access”

AlopeciaDet accurately detects Alopecia Areata early using advanced image analysis.

research 731 Generation of a laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists created a detailed map of gene activity in different parts of human hair follicles.

research Association of Dihydrotestosterone with Crowing Complexity Traits in Kokok Balenggek Roosters

May 2026 in “International Journal of Veterinary Science”

Higher dihydrotestosterone levels reduce crowing complexity in Kokok Balenggek roosters.

research Research on the Quality Differences between Male and Female Plants of Gynostemma longipes Based on Broad Target Metabolomics

November 2025

Male and female Gynostemma longipes plants have significant chemical differences.

research Hypoparathyroidism as the single major component for decades of autoimmune polyglandular syndrome type 1

2 citations , December 2020 in “Endocrinology, diabetes & metabolism case reports”

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

research Analysis of the Working Principle of Hair Dye

June 2026 in “Applied and Computational Engineering”

Understanding different hair dye types can make them safer and better.

Sample Collecting Methods for Bacterial Community Structure Analysis of Scalp Hair: Non-Invasive Swabbing Versus Intrusive Hair Shaft Cutting

research Sample collecting methods for bacterial community structure analysis of scalp hair: non-invasive swabbing versus intrusive hair shaft cutting

1 citations , September 2024 in “Scientific Reports”

Non-invasive swabbing is as effective as cutting hair for collecting scalp hair bacteria.

research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses

March 2024 in “medRxiv (Cold Spring Harbor Laboratory)”

Recent selection on immune response genes was identified across seven ethnicities.

research Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis

January 2026 in “Frontiers in Nutrition”

Certain dietary supplements can improve hair density and are well-tolerated for treating androgenetic alopecia.

research The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization

131 citations , July 2009 in “Experimental Dermatology”

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

research Comparative transcriptomic analysis of dermal wound healing reveals de novo skeletal muscle regeneration in Acomys cahirinus

24 citations , May 2019 in “PLOS ONE”

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

research Genomic Analysis of Trichotillomania

1 citations , January 2025 in “medRxiv”

Trichotillomania may have a genetic link to psychiatric disorders.

Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product Demonstrating Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial

research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial

March 2026 in “Preprints.org”

The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.

research Transcriptomic Analysis Provides Molecular Insights into Skin Development in Dezhou Donkey Foals

January 2026 in “Veterinary Sciences”

Skin maturation in Dezhou donkey foals involves better barrier function, hair growth, and less collagen production.

research Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease

17 citations , June 2023 in “Pharmaceuticals”

Inflammasome proteins may help diagnose and treat Parkinson's disease.

research The composition of cell‐based therapies obtained from point‐of‐care devices/systems which mechanically dissociate lipoaspirate: a scoping review of the literature

8 citations , January 2022 in “Journal of Experimental Orthopaedics”

It's unclear if cell-based therapies from lipoaspirate devices improve clinical outcomes due to inconsistent data.

research Group-ICA Model Order Highlights Patterns of Functional Brain Connectivity

109 citations , January 2011 in “Frontiers in Systems Neuroscience”

Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.

research Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea

September 2022 in “Research Square (Research Square)”

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

research The Potential of Moringa (Moringa oleifera Lamk) Seed Oil as Anti- Alopecia

May 2022 in “Pharmacognosy journal”

Moringa seed oil may help prevent hair loss and promote hair growth.

research Capsaicin: an in-depth review of its chemical properties, health benefits, and challenges in food applications

2 citations , September 2025 in “Food Production Processing and Nutrition”

Capsaicin offers health benefits and flavor but faces challenges in food use.

research Systematic investigation of a potential epidemiological and genetic association between male androgenetic alopecia and COVID‐19

2 citations , October 2021 in “Skin health and disease”

No significant link between male pattern baldness and COVID-19 severity was found.