research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
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810-840 / 1000+ results research When the Circadian Clock Meets the Melanin Pigmentary System
Silencing certain circadian clock genes increases skin pigmentation.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research A role of melatonin in neuroectodermal‐mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors
Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
research The Influence of Flightless I: Regeneration versus Wound Healing
Blocking RANK signaling might help treat metastatic melanoma, but more research is needed.
research 503 A new chemosensory control of human hair growth: Olfactory receptor OR10J1 stimulation promotes scalp hair follicle growth and progenitor cell generation ex vivo
Stimulating OR10J1 can promote hair growth and may help treat hair loss.
research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B1
Synthetic hormone treatment reduces melanin and hair growth in rats.
research The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system
Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
research Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
research Inducible cre-mediated N-ras activation and PTEN inactivation in transgenic mouse melanocytes requires keratinocyte hyperplasia to elicit a melanocyte pathology
Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
research Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
research The existence of a linear system consisting of sympathetic endings in rat skin
Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
research 085 Autoantigen screening in C3H/HeJ mouse model of alopecia areata revealed high antigenicity of melanocyte-associated antigen epitopes
Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
research Porokeratotic adnexal ostial nevus: a paradigm of cutaneous mosaicism
PAON shows skin patterns due to genetic mosaicism.
research Melatonin-induced inhibition of melanogenesis in hair follicles in vitro [proceedings].
research Gene Expression Profiles of Melanocytes Over-Expressing miR-5110 in Alpaca
miR-5110 affects alpaca pigmentation by altering specific gene expressions.
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Editor's evaluation: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
research ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype
Stromal cells in melanoma promote tumor growth and spread.
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Any route for melanoblasts to colonize the skin!
Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
research The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth
Muscarinic acetylcholine receptors in skin cells help regulate and promote hair growth.
research Increased expression of the gene for the Y1 receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y1R/LacZ transgenic mice in response to restraint stress
Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C
Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
research Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats
Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
research 700 Oncostatin M is upstream of JAK-STAT signaling during the murine hair cycle
Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
research Melatonin and the hair follicle
Melatonin helps regulate hair growth and protects the hair follicle from stress.
research Research on Expression of Retinoid-related Orphan Receptor (ROR) in the Skin of Cashmere Goat
RORs may influence cashmere growth cycles.