January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
March 2024 in “Middle East Fertility Society Journal/Middle East Fertility Society Journal ” PCOS patients have more central body fat, which can be effectively measured using DEXA.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
49 citations
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September 2015 in “Psychoneuroendocrinology” 5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
17 citations
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January 2020 in “The World Journal of Men's Health” Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
11 citations
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October 2002 in “Pharmacology Biochemistry and Behavior” Formalin-induced pain increases testosterone breakdown in the rat brain and spinal cord.
9 citations
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May 2024 in “Journal of Clinical & Translational Endocrinology” Gender affirming hormone therapy improves outcomes in gender affirmation surgery.
7 citations
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June 2024 in “iScience” Androgens increase cervical cancer risk and affect its development.
6 citations
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July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
4 citations
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August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.