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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A woman developed male characteristics after using unregulated hormone therapy.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

Some hormone treatments might raise breast cancer risk, while others don't seem to.

The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.

The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.

Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Prostaglandins may contribute to male hair loss; targeting them could help treat it.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

PRP preparation partially activates platelets, causing varied growth factor release.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

Hormonal birth control can cause skin issues, but low-dose options and those with antiandrogens may reduce these effects.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Control variability makes it hard to confirm low-dose endocrine effects.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

The ovary mainly causes high testosterone in PCO, while the adrenal gland is the main source in IH.

Compounds from Pterocarpus indicus may help treat benign prostatic hyperplasia by stopping cell growth.

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

Bone mineral and minocycline boost bone cell growth, aiding healing.

Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

Including androgens in hormone therapy may lower breast cancer risk.

HPV infection is linked to better survival in advanced anal cancer, higher radiation doses improve survival, especially in HPV-negative patients, and prostaglandin E₂ pretreatment can protect mouse hair follicles from radiation damage.

PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.