January 2023 in “Journal of orthopedics & bone disorders” Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.
April 2018 in “Journal of Investigative Dermatology” DNMT3A is crucial for healthy skin and hair growth.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
44 citations
,
May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
39 citations
,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
31 citations
,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
28 citations
,
August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
18 citations
,
January 2019 in “Animal Biotechnology” A newly found RNA in Cashmere goats may play a role in hair growth and development.
4 citations
,
January 2025 in “International Journal of Molecular Sciences” Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
February 2026 in “Advanced Science” TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
September 2025 in “Development” Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
277 citations
,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
51 citations
,
April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
29 citations
,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
27 citations
,
April 2020 in “Molecular Biology and Evolution” Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
13 citations
,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
7 citations
,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
5 citations
,
November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
3 citations
,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
1 citations
,
May 2023 in “Frontiers in Pharmacology” Millet seed oil may help hair grow by activating certain cell growth signals.
1 citations
,
October 2022 in “Bioengineering” Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
January 2020 in “Journal of Entomology and Zoology Studies” Canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
144 citations
,
June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
71 citations
,
May 1991 in “Clinical and Experimental Dermatology” Young men with male pattern baldness lose hair density over time without treatment.
30 citations
,
July 2004 in “Fertility and Sterility” Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
26 citations
,
June 2022 in “Stem Cell Research & Therapy” Tideglusib helps heal wounds in older skin.