34 citations
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October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
33 citations
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June 1995 in “Journal of Pharmaceutical Sciences” More ethanol increases minoxidil delivery, but too much lowers efficiency.
7 citations
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February 2019 in “Journal of Molecular Liquids” Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.
5 citations
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August 2014 in “Pharmaceutical Development and Technology” Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
1 citations
,
March 2024 in “International Journal of Applied Pharmaceutics” Propylene glycol concentration improves rice water gel shampoo's thickness and foam, extending its shelf life.
January 2021 in “Journal of clinical & experimental dermatology research” The new 5% minoxidil formulation without propylene glycol effectively promotes hair growth with fewer side effects and better user satisfaction.
October 2017 in “Our Dermatology Online” DCP in isopropanol is better tolerated for treating alopecia areata.
January 2017 in “Nasza Dermatologia Online” Both treatments helped hair regrowth in alopecia areata, with isopropanol being better tolerated.
May 2023 in “International Journal of Trichology” A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
January 2021 in “Medical research archives” The 5% minoxidil lotion without propylene glycol is effective, well-tolerated, and cosmetically acceptable for hair loss.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
September 2019 in “Case medical research” June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
The best mix of propylene glycol and sorbitol was found for a cream to prevent hair loss using saw palmetto extract.
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123 citations
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February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
69 citations
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February 1987 in “Archives of Dermatology” Topical cyclosporine lotion led to hair regrowth in a man with alopecia universalis.
68 citations
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March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
55 citations
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June 2009 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
39 citations
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April 2010 in “International Journal of Pharmaceutics” Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
38 citations
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June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
34 citations
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September 1985 in “Contact Dermatitis” Minoxidil can cause skin irritation like eczema and rash in some users.
32 citations
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May 1995 in “Contact Dermatitis” Minoxidil can cause allergic reactions, but testing helps identify the cause.
29 citations
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August 1985 in “Contact Dermatitis” Minoxidil can cause allergic reactions like burning, itching, and red bumps.
28 citations
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November 2020 in “Fluid Phase Equilibria” Minoxidil dissolves better in propylene glycol + water than in supercritical CO2.
16 citations
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December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
16 citations
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January 2007 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.
15 citations
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February 2023 in “Colloids and surfaces. B, Biointerfaces” Smaller curcumin nanocrystals penetrate skin better, but additives and particle size affect absorption and accumulation.
15 citations
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February 1987 in “Archives of Dermatology” Topical cyclosporine lotion led to noticeable hair regrowth in alopecia universalis.
14 citations
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January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.