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Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.

The research identified genes and non-coding RNAs in cells that could be affected by testosterone, which may help understand hair loss and prostate cancer.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

GPR40 agonists help hair growth through the protein ANGPTL4.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

Early hormones shape sex-specific differences in rat glands.

Lysophospholipids can act as anti-inflammatory agents through specific receptors, but more research is needed.

Low-penetration genes might help personalize colorectal cancer prevention.

Targeting the p300/AR axis may help treat polycystic ovary syndrome.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Certain gene combinations may affect prostate cancer risk, and GSTP1 methylation is linked to tumor aggressiveness.

Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

Certain gene variations are significantly linked to hair loss, especially in white people.

Analog 23 is a promising compound for prostate cancer treatment.

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

Androgen increases VEGF expression but not VEGFR-2 in rat corpus cavernous.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.