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Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.

Early hormones shape sex-specific differences in rat glands.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.

Inhibiting certain enzymes made female rats more sensitive to low-level pain.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.

Some dibenzo compounds might help treat cancer with fewer side effects.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

These medications for BPH have known risks and may have new side effects.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Androgen receptor overexpression can increase prostate cancer cell growth even without hormones.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Finasteride increases P-glycoprotein activity in the liver and kidney.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.