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GlossaryProstate Weight

mass of prostate gland, usually measured in grams

Prostate weight refers to the mass of the prostate gland, typically measured in grams. This measurement is important in medical contexts, as an enlarged prostate can indicate conditions such as benign prostatic hyperplasia (BPH) or prostate cancer. For professionals, accurate assessment of prostate weight can aid in diagnosis, treatment planning, and monitoring the effectiveness of therapeutic interventions.

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Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats

research Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats

August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences”

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

research Relative binding affinity of novel steroids to androgen receptors in hamster prostate

5 citations , January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

New steroids were effective in blocking male hormone receptors in hamster prostates.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations , March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

research Characteristics of flutamide action on prostatic and testicular functions in the rat

30 citations , June 1988 in “Journal of Steroid Biochemistry”

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors

22 citations , June 2002 in “Journal of Medicinal Chemistry”

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors

13 citations , January 2005 in “Chemical and Pharmaceutical Bulletin”

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats

8 citations , May 2011 in “Journal of Pharmacology and Experimental Therapeutics”

Dosing time affects finasteride's effectiveness and safety in rats.

research Scientific Evaluation of A Unani Pharmacopoeia-Based Formulation on BPH in Animal Model

2 citations , November 2023 in “International Journal of Preventive Medicine and Health (IJPMH)”

The Unani Pharmacopoeia-Based Formulation significantly improved symptoms of enlarged prostate in rats.

research Effect of Exogenous Testosterone, Finasteride, and Castration on serum level of Thyroxin

1 citations , August 2013 in “PubMed”

Testosterone changes reduce thyroxin levels in rats.

Hepatoprotective and Anti-Hyperplastic Effects of Silver Nanoparticles Biosynthesized Using Aqueous Extracts of Mitracarpus Scaber: Insights from Acetaminophen and Testosterone Experimental Models

research Hepatoprotective and anti-hyperplastic effects of silver nanoparticles biosynthesised using aqueous extracts of M. scaber : Insights from acetaminophen and testosterone experimental models

January 2026 in “E3S Web of Conferences”

Silver nanoparticles from Mitracarpus scaber protect the liver and reduce prostate enlargement.

research 1748 IS ANDROGENETIC ALOPECIA ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA? ANALYSIS OF 907 PATIENTS

March 2013 in “The Journal of Urology”

Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.

research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

17 citations , June 2012 in “European journal of medicinal chemistry”

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment

26 citations , July 1995 in “Neurobiology of Aging”

Finasteride affects prostate weights and pituitary activity differently with age.

research 411 THE POTENTIAL OF CIRCULATING ENDOTHELIAL CELLS AS PROGNOSTIC BIOMARKERS IN PROSTATE CANCER

March 2011 in “European Urology Supplements”

CEC levels may be a useful marker for predicting prostate cancer progression.

Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats

research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D₂ synthase expression in adult rats

14 citations , June 2015 in “Toxicology and Industrial Health”

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

research Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate

2 citations , January 2011 in “Andrologia”

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Effects of Combined Therapy of D-004 and Finasteride on Testosterone-Induced Prostate Hyperplasia in Rats

research Efectos de la terapia combinada del D-004 y el Finasteride sobre la hiperplasia de próstata inducida por testosterona en ratas

January 2007 in “El Servicio de Difusión de la Creación Intelectual (National University of La Plata)”

Combining D-004 and finasteride is more effective at reducing prostate enlargement than using either alone.

research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice

91 citations , July 2004 in “Journal of Biological Chemistry”

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception

research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1

14 citations , December 1998 in “The Journal of Clinical Endocrinology and Metabolism”

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

research Impact of androgen deprivation therapy on mortality of prostate cancer patients with COVID-19: a propensity score-based analysis

9 citations , November 2021 in “Infectious Agents and Cancer”

Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.

research Inhibition of 5α-reductase in the rat prostate by Cimicifuga racemosa

7 citations , August 2006 in “Maturitas”

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

An Overview of Chemotherapy Side Effects on Patients with Prostate Cancer, Bladder Cancer, and Testicular Cancer at Haji Adam Malik General Hospital Medan from 2020-2022

research An Overview of Chemotherapy Side Effects on Patients with Prostate Cancer, Bladder Cancer, and Testicular Cancer at Haji Adam Malik General Hospital Medan from 2020-2022

1 citations , May 2023 in “Jurnal Kedokteran Diponegoro”

Chemotherapy for prostate, bladder, and testicular cancer patients commonly causes hair loss, fatigue, and decreased appetite.

research Finasteride-its impact on sexual function and prostate cancer

33 citations , January 2009 in “Journal of Cutaneous and Aesthetic Surgery”

Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.

research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia

44 citations , January 2012 in “Food and chemical toxicology”

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone

28 citations , November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The normal human prostate does not significantly affect blood DHT levels.

research Additive in vivo growth-inhibitory effects of flutamide and finasteride on androgen-sensitive Shionogi 115 carcinoma

6 citations , January 1996 in “Endocrine-related Cancer”

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Ganoderma Lucidum as an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats

research Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies

1 citations , June 2025 in “Scientific Reports”

Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.