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New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

New Finasteride conjugate improves prostate treatment and vital signs in rats.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Ultra-high molecular weight poly-γ-glutamic acid may help promote hair growth.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Red ginseng oil improves urinary symptoms and some sexual functions in men safely.

USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Finasteride may reduce bleeding after TURP, but more research needed.

Wedelolactone selectively kills prostate cancer cells without harming normal cells.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Circadian rhythm disruption, chronic inflammation, hormones, metabolism, and genetics may increase prostate cancer risk.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

Ezetimibe effectively reduces prostate size in cases of benign prostatic hyperplasia.

Finasteride before TURP reduces blood loss and slightly improves early postoperative quality of life.

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

Diabetes may lower the risk of prostate cancer.

Finasteride is popular for treating male hair loss but may increase the risk of serious prostate cancer and has other potential side effects.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.