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GlossaryProstate Weight

mass of prostate gland, usually measured in grams

Prostate weight refers to the mass of the prostate gland, typically measured in grams. This measurement is important in medical contexts, as an enlarged prostate can indicate conditions such as benign prostatic hyperplasia (BPH) or prostate cancer. For professionals, accurate assessment of prostate weight can aid in diagnosis, treatment planning, and monitoring the effectiveness of therapeutic interventions.

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research Effect of the ethanol extract of Syzygium aromaticum (clove) leaves on the lipid profile and body weight in testosterone-induced benign prostatic hyperplasia rats

May 2026 in “Global Translational Medicine”

Clove leaf extract lowers bad cholesterol and increases good cholesterol while also increasing body weight.

research Characteristics of flutamide action on prostatic and testicular functions in the rat

30 citations , June 1988 in “Journal of Steroid Biochemistry”

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats

research Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats

August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences”

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

research 1748 IS ANDROGENETIC ALOPECIA ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA? ANALYSIS OF 907 PATIENTS

March 2013 in “The Journal of Urology”

Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.

research Relative binding affinity of novel steroids to androgen receptors in hamster prostate

5 citations , January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

New steroids were effective in blocking male hormone receptors in hamster prostates.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations , March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors

22 citations , June 2002 in “Journal of Medicinal Chemistry”

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors

13 citations , January 2005 in “Chemical and Pharmaceutical Bulletin”

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats

8 citations , May 2011 in “Journal of Pharmacology and Experimental Therapeutics”

Dosing time affects finasteride's effectiveness and safety in rats.

research Scientific Evaluation of A Unani Pharmacopoeia-Based Formulation on BPH in Animal Model

2 citations , November 2023 in “International Journal of Preventive Medicine and Health (IJPMH)”

The Unani Pharmacopoeia-Based Formulation significantly improved symptoms of enlarged prostate in rats.

Hepatoprotective and Anti-Hyperplastic Effects of Silver Nanoparticles Biosynthesized Using Aqueous Extracts of Mitracarpus Scaber: Insights from Acetaminophen and Testosterone Experimental Models

research Hepatoprotective and anti-hyperplastic effects of silver nanoparticles biosynthesised using aqueous extracts of M. scaber : Insights from acetaminophen and testosterone experimental models

January 2026 in “E3S Web of Conferences”

Silver nanoparticles from Mitracarpus scaber protect the liver and reduce prostate enlargement.

research Effect of Exogenous Testosterone, Finasteride, and Castration on serum level of Thyroxin

1 citations , August 2013 in “PubMed”

Testosterone changes reduce thyroxin levels in rats.

research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

17 citations , June 2012 in “European journal of medicinal chemistry”

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment

26 citations , July 1995 in “Neurobiology of Aging”

Finasteride affects prostate weights and pituitary activity differently with age.

Ganoderma Lucidum as an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats

research Ganoderma lucidum is an inhibitor of testosterone-induced prostatic hyperplasia in rats

24 citations , June 2011 in “Andrologia”

Ganoderma lucidum may help treat enlarged prostate in rats.

research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia

16 citations , January 2019 in “Pharmaceutical biology”

Lespedeza cuneata extract may help treat enlarged prostate.

research Inhibitory effects of TripTripterygium wilfordii multiglycoside on benign prostatic hyperplasia in rats

5 citations , June 2015 in “Chinese journal of natural medicines/Zhongguo tianran yaowu/Chinese Journal of Natural Medicines”

Tripterygium wilfordii multiglycoside effectively reduced prostate enlargement in rats without harmful effects.

Hydroxychloroquine Modulates the Progression of Experimentally Induced Benign Prostatic Hyperplasia in Rats via Targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL Pathways: Computational and In Vivo Studies

research Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies

1 citations , June 2025 in “Scientific Reports”

Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.

research 411 THE POTENTIAL OF CIRCULATING ENDOTHELIAL CELLS AS PROGNOSTIC BIOMARKERS IN PROSTATE CANCER

March 2011 in “European Urology Supplements”

CEC levels may be a useful marker for predicting prostate cancer progression.

Administration of Caesalpinia Bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia in Male Wistar Rats

research Administration of Caesalpinia bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats

6 citations , May 2022 in “Research and reports in urology”

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

research Pharmacological Effects of the Lipidosterolic Extract from Kigelia africana Fruits in Experimental Benign Prostatic Hyperplasia Induced by Testosterone in Sprague Dawley Rats

3 citations , February 2023 in “Journal of Experimental Pharmacology”

Kigelia africana fruit extract can prevent and reverse prostate enlargement in rats.

research Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase

43 citations , August 2016 in “Scientific Reports”

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.

research Spermatogenic and Androgenic Potential of Nephrolepis biserrata on Testosterone- Propionate Induced Benign Prostatic Hyperplasia In Male Wistar Rats

January 2024 in “Journal of Applied Health Sciences and Medicine”

Nephrolepis biserrata may improve fertility and reduce prostate issues in males.

research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice

91 citations , July 2004 in “Journal of Biological Chemistry”

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia

44 citations , January 2012 in “Food and chemical toxicology”

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats

research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D₂ synthase expression in adult rats

14 citations , June 2015 in “Toxicology and Industrial Health”

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception

research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1

14 citations , December 1998 in “The Journal of Clinical Endocrinology and Metabolism”

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Effect of Finasteride on Serum Concentrations of Dihydrotestosterone and Testosterone in Three Clinically Normal Sexually Intact Adult Male Dogs

research Effect of finasteride on serum concentrations of dihydrotestosterone and testosterone in three clinically normal sexually intact adult male dogs.

10 citations , June 1998 in “PubMed”

Finasteride significantly reduces DHT levels in male dogs without affecting testosterone levels, suggesting it could be used to treat benign prostatic hypertrophy in dogs weighing 10 to 50 kilograms.

research Impact of androgen deprivation therapy on mortality of prostate cancer patients with COVID-19: a propensity score-based analysis

9 citations , November 2021 in “Infectious Agents and Cancer”

Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.

research Inhibition of 5α-reductase in the rat prostate by Cimicifuga racemosa

7 citations , August 2006 in “Maturitas”

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.