2 citations
,
November 2025 in “Biomedicines” This review discusses the dual regenerative and antimicrobial properties of platelet- and marrow-derived biologics, such as PRP and BMAC, which are used in tissue repair and regeneration. These biologics promote healing and reduce infection risk through growth factors, cytokines, and cellular components. They show significant regenerative effects in musculoskeletal conditions, wound healing, and cartilage repair. However, clinical outcomes are affected by preparation methods, patient factors, and lack of standardization. Despite their potential to reduce reliance on pain medications and improve function, these therapies face challenges like inconsistent protocols, limited long-term safety data, and regulatory issues. The review emphasizes the need for standardized procedures and further research to optimize their clinical use in pain medicine.
21 citations
,
December 2006 in “Archives of dermatology” A kidney transplant patient developed pink skin bumps with spiny centers on her face and limbs.
101 citations
,
December 2014 in “Stem Cells and Cloning Advances and Applications” Oral stem cells show promise for tissue repair, but more human trials are needed.
January 2018 in “Georg Thieme Verlag eBooks” Gender affirmation surgery improves personal appearance and self-esteem.
38 citations
,
March 2019 in “International Wound Journal” A new skin treatment using a patient's own cells healed chronic wounds effectively and was preferred over traditional grafts.
Synthetic hairs can help in restoring lost hair.
June 2023 in “Research Square (Research Square)” Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
4 citations
,
October 2015 in “JAAD Case Reports” Surgical grafting may fix nail issues caused by valproic acid.
2 citations
,
June 2025 in “Chemical Engineering Journal” The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
December 2022 in “Molecular Pharmaceutics” Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
1 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
December 2020 in “Nippon Laser Igakkaishi” Photobiomodulation therapy is beneficial in plastic surgery and dermatology.
70 citations
,
February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
June 2026 in “Frontiers in Materials” Smart hydrogel dressings can improve healing for severe wounds by mimicking natural tissue and delivering treatments.
4 citations
,
May 2023 in “Composites Part B: Engineering” The nanocomposite hydrogels can repair themselves, change shape, reduce inflammation, protect against oxidation, kill bacteria, stop bleeding, and help heal diabetic wounds while allowing for wound monitoring.
1 citations
,
February 2026 in “ACS Nano” The study presents the development of the TLMG hydrogel, a biointerface platform that forms in situ and adheres robustly to irregular skin wounds, offering enhanced mechanical properties and real-time signal monitoring for advanced wound management. By integrating tea polyphenols/lignin microspheres, the hydrogel combines bioelectronic and bioactive interfaces, achieving strong adhesion (200 kPa), high ionic conductivity (0.27 mS cm–1), and mechanical stability. Tested in complex animal models and human trials, the TLMG platform demonstrated intelligent wound management, dynamic signal monitoring, and improved wound healing through immunomodulatory mechanisms, highlighting its potential for wearable healthcare systems.
30 citations
,
February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
24 citations
,
October 2024 in “International Journal of Extreme Manufacturing” 3D skin bioprinting has advanced but still faces challenges like safety and the need for better integration with sensors.
198 citations
,
May 2021 in “Advanced Materials” Triboelectric nanogenerators can use body movement to power therapeutic treatments, potentially transforming personalized healthcare.
September 2023 in “International Journal of Science and Research (IJSR)” PRP and PRF can effectively heal chronic wounds.
October 2013 in “Revue de Chirurgie Orthopédique et Traumatologique”
5 citations
,
December 2011 in “Canadian Journal of Plastic Surgery” Hair grafts can successfully reconstruct a beard on reconstructed jaw skin, improving appearance and patient satisfaction.
29 citations
,
January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
The hydrogel treatment speeds up healing of diabetic wounds.
Keratin gel may help repair damaged nerves.
12 citations
,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
1 citations
,
August 2023 in “International Journal of Surgery Case Reports” Using titanium mesh and thigh tissue is effective for complex scalp reconstruction.
17 citations
,
December 2022 in “Biosensors” Triboelectric nanogenerators can power wearable medical devices for long-term self-treatment and monitoring.
4 citations
,
January 2013 in “Inflammation and Regeneration” Stem cell-based therapies can regenerate and replace teeth effectively.
March 2021 in “Institutional Repositories DataBase (IRDB)” Heparin-functionalized nanofabrics help heal wounds effectively and safely without scars in 14 days.