CD28 is a promising target for treating alopecia areata with belatacept.
March 2026 in “Skin Appendage Disorders” Belatacept may be a promising treatment for alopecia areata.
October 2023 in “International journal of molecular sciences” Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
January 2022 in “Mammalian Genome” The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.
56 citations
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October 2007 in “Journal of Biological Chemistry” Cathepsin L is essential for heart health and its absence causes heart problems and hair loss.
37 citations
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December 1995 in “Journal of Cell Science” Nexin 1 may help control hair growth.
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May 1999 in “Biochemical and Biophysical Research Communications” A new enzyme, BSSP, is found in high amounts in the hair follicles of nude mice.
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August 1999 in “Journal of Investigative Dermatology” Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.
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February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.
6 citations
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September 2020 in “Journal of The American Academy of Dermatology” Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.
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July 2023 in “Forensic science international. Genetics” Hair protein analysis might help identify a person's ethnicity, sex, and age in forensics.
1 citations
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September 2001 in “PubMed” ONO-3403 effectively reduces mouse skin tumor growth without side effects.
December 2023 in “Sains Malaysiana” The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.
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April 2017 in “Scientific Reports” Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
54 citations
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January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
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January 2004 in “European Journal of Cell Biology” Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.
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March 2017 in “Scientific Reports” HAT-L4 is crucial for preventing body fluid loss by maintaining skin barrier integrity.
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March 2019 in “PLoS ONE” A new method improves protein analysis in hair, aiding health and disease research.
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October 2006 Matriptase imbalance contributes to cancer development and spread.
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August 2018 in “Journal of Investigative Dermatology” 8 citations
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October 2006 in “Current Pharmaceutical Design” Common gene patterns may cause skin autoimmune diseases.
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April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
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September 2004 in “International Journal of Cosmetic Science” Hair quality is genetically determined and linked to its composition and strength.
August 2025 in “Scientific Reports” C4BPA protein may link acne severity and insulin resistance.
December 2022 in “Biochemical and Biophysical Research Communications” HtrA2 activity is crucial for normal hair growth by regulating fat cell development.
August 2015 in “Free Radical Biology and Medicine” The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.
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April 2012 in “Molecular Biology Reports” The enzyme from Bacillus cereus can be used in detergents and leather processing.
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November 2018 in “Genetics in medicine” Lack of cystatin M/E causes thin hair and dry skin.
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April 2022 in “Frontiers in cell and developmental biology” The research identified key proteins and genes that may influence wool bending in goats.