1 citations
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December 2016 Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
Removing SIX1 in fat cells reduces skin fibrosis.
October 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and optimizing treatment outcomes.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
October 2022 in “Journal of experimental and clinical medicine” Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.
February 2022 in “Research Square (Research Square)” Key genes influencing sheep hair follicle development were identified, aiding wool breeding and understanding human hair conditions.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
149 citations
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July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
91 citations
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May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
82 citations
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March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
62 citations
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August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
55 citations
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March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
39 citations
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January 2020 in “Scientific Reports” Four circRNAs were found to be significantly different in cashmere goat skin, affecting cashmere fineness.
32 citations
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February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
30 citations
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April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
24 citations
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May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
22 citations
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June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
17 citations
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September 2022 in “Genes & Genomics” Long non-coding RNAs affect feather growth in chickens in ways that don't follow traditional genetic rules.
15 citations
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December 2017 in “Journal of Investigative Dermatology” No strong genetic link to other skin conditions was found, but some genetic factors may make people more likely to get seborrheic dermatitis.
11 citations
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August 2015 in “PLOS ONE” Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.
9 citations
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July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
6 citations
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March 2019 in “Dermatologic surgery” Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
5 citations
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February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
4 citations
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September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia” Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.
4 citations
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October 2019 in “Skin appendage disorders” PRP injections safely increase hair density and thickness in androgenetic alopecia.